Actively Recruiting
Effect of Limb Length Ratio on Roux-en-Y Gastric Bypass Outcomes (CLIMB II Study)
Led by Salvador Navarrete · Updated on 2026-03-20
262
Participants Needed
1
Research Sites
360 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The investigators propose a randomized controlled trial comparing BP and roux limb lengths measuring 30 and 15% respectively of patient's total small bowel length versus current standard practice using fixed lengths. The findings would provide further insight into feasibility of standardizing RYGB limb lengths and optimizing resultant weight loss and metabolic effects. The investigators hypothesize RYGB with ratio-adjusted limb lengths (aRYGB) will result in higher total weight loss and resolution of metabolic syndrome comorbidities, including diabetes, hyperlipidemia, and hypertension compared to standard fixed-length RYGB (sRYGB). The study will also utilize the Short Form Rand 36-Item Health Survey (SF36) to determine differences in postoperative quality of life metrics.
CONDITIONS
Official Title
Effect of Limb Length Ratio on Roux-en-Y Gastric Bypass Outcomes (CLIMB II Study)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Morbidly obese patients with a BMI between 40 and 60
- Patients who understand and accept the need for long-term follow-up
- Patients who agree to be included in the study
You will not qualify if you...
- Individuals unable to understand and sign a written consent form
- Patients with a history of previous bariatric surgery procedures
- Presence of a severe and life-threatening condition unrelated to obesity
- Previous gastric or small bowel resection
- Active cancer
- Pregnancy or desire to become pregnant during the study
- Mentally unbalanced patients under supervision or guardianship or unable to give consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Cleveland clinic
Cleveland, Ohio, United States, 44195
Actively Recruiting
Research Team
S
Salvador Navarrete, MD
CONTACT
A
Andrew Strong, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here