Actively Recruiting
The Effect of Mechanical Ventilation on Radiofrequency Ablation in the Treatment of Atrial Fibrillation
Led by Kocaeli City Hospital · Updated on 2025-01-24
50
Participants Needed
1
Research Sites
30 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating how different mechanical ventilation methods affect the success of radiofrequency ablation (RFA) in treating atrial fibrillation (AF). RFA is performed under general anesthesia, and the procedure's success depends on stable and safe contact between the catheter electrode and heart muscle. Movement caused by breathing can reduce catheter stability, leading to less effective treatment and higher chances of AF returning. Although some ventilation methods like high-frequency jet ventilation have shown promise in improving catheter stability and reducing AF recurrence, no clear evidence currently exists about which ventilation mode is best during RFA. The study compares two mechanical ventilation strategies used during RFA under general anesthesia: Flow Controlled Ventilation (FCV) and Volume Controlled Ventilation (VCV). Participants receive radiofrequency ablation for AF while connected to one of these ventilation modes. The hospital's equipment supports various ventilation types, but high-frequency jet ventilation is not available. The goal is to see if one ventilation method improves the procedure by enhancing catheter contact and stability. Participants will be monitored during and after the ablation procedure. Key outcomes measured include the duration of the ablation procedure, changes in electrocardiography at the procedure's end, and the rate of atrial fibrillation recurrence one month after treatment. Researchers will assess these factors to determine how ventilation affects ablation effectiveness and safety. The entire evaluation focuses on treatment success and patient outcomes following the procedure.
CONDITIONS
Official Title
Effect of Mechanical Ventilation on Radiofrequency Ablation in Atrial Fibrillation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with atrial fibrillation
- Planned to receive radiofrequency ablation treatment under general anesthesia
- All patients over 18 years of age
You will not qualify if you...
- Patients undergoing ablation under sedation and/or local anesthesia
AI-Screening
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Trial Site Locations
Total: 1 location
1
Kocaeli City Hospital
Kocaeli, Turkey (Türkiye)
Actively Recruiting
Research Team
M
Merve Yazici Kara
N
Nurseda Dundar
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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