Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
ID06791915

The Effect of Mechanical Ventilation on Radiofrequency Ablation in the Treatment of Atrial Fibrillation

Led by Kocaeli City Hospital · Updated on 2025-01-24

50

Participants Needed

1

Research Sites

30 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating how different mechanical ventilation methods affect the success of radiofrequency ablation (RFA) in treating atrial fibrillation (AF). RFA is performed under general anesthesia, and the procedure's success depends on stable and safe contact between the catheter electrode and heart muscle. Movement caused by breathing can reduce catheter stability, leading to less effective treatment and higher chances of AF returning. Although some ventilation methods like high-frequency jet ventilation have shown promise in improving catheter stability and reducing AF recurrence, no clear evidence currently exists about which ventilation mode is best during RFA. The study compares two mechanical ventilation strategies used during RFA under general anesthesia: Flow Controlled Ventilation (FCV) and Volume Controlled Ventilation (VCV). Participants receive radiofrequency ablation for AF while connected to one of these ventilation modes. The hospital's equipment supports various ventilation types, but high-frequency jet ventilation is not available. The goal is to see if one ventilation method improves the procedure by enhancing catheter contact and stability. Participants will be monitored during and after the ablation procedure. Key outcomes measured include the duration of the ablation procedure, changes in electrocardiography at the procedure's end, and the rate of atrial fibrillation recurrence one month after treatment. Researchers will assess these factors to determine how ventilation affects ablation effectiveness and safety. The entire evaluation focuses on treatment success and patient outcomes following the procedure.

CONDITIONS

Official Title

Effect of Mechanical Ventilation on Radiofrequency Ablation in Atrial Fibrillation

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with atrial fibrillation
  • Planned to receive radiofrequency ablation treatment under general anesthesia
  • All patients over 18 years of age
Not Eligible

You will not qualify if you...

  • Patients undergoing ablation under sedation and/or local anesthesia

AI-Screening

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Trial Site Locations

Total: 1 location

1

Kocaeli City Hospital

Kocaeli, Turkey (Türkiye)

Actively Recruiting

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Research Team

M

Merve Yazici Kara

N

Nurseda Dundar

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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