Study of Mechanical Ventilation Methods During Radiofrequency Ablation for Atrial Fibrillation Under General Anesthesia

What this Trial Is About

Researchers are studying the effects of different mechanical ventilation methods on radiofrequency ablation RFA treatment for atrial fibrillation AF. This study focuses on how controlled breathing affects catheter stability and contact force during the procedure, which are crucial for successful energy delivery to heart tissue and long-lasting pulmonary vein isolation PVI. The trial compares ventilation methods used during general anesthesia to determine their impact on procedural success and AF recurrence. Participants will receive radiofrequency ablation under general anesthesia using one of two mechanical ventilation modes Flow Controlled Ventilation FCV or Volume Controlled Ventilation VCV. Both methods involve controlled breathing to reduce thoracic movement and improve catheter contact with the heart tissue. The study records ventilation settings, heart and respiratory measurements, and ablation lesion details such as ablation time, contact force, and impedance drop. Clinical outcomes including freedom from arrhythmias and procedural complications will be tracked during follow-up. During the study, participants will undergo monitoring of vital signs and ventilation parameters alongside detailed recording of ablation procedure characteristics. Researchers will measure the duration of the ablation procedure, changes in electrocardiography from baseline, and the rate of atrial fibrillation recurrence one month after the treatment. The study aims to gather data on procedural efficiency and safety, with follow-up evaluations to assess long-term effects. Total ablation time varies between 1 and 3 hours depending on the procedure.

Effect of Mechanical Ventilation on Radiofrequency Ablation in Atrial Fibrillation