Studying the Effects of a Mediterranean Diet on Adults with Inflammatory Bowel Disease

What this Trial Is About

Researchers are studying how diet affects inflammatory bowel disease IBD, focusing on how dietary changes may influence the severity of IBD symptoms. This study aims to better understand the impact of diet on inflammation and disease activity in patients with IBD, including those with Crohns Disease. The University of California, San Diego is leading this research to explore these effects using biological samples and disease markers. Participants will follow a Mediterranean Diet for 42 days as the main intervention. During this period, the diets influence on the patients health will be monitored through various tests, including blood and stool sample collections. These samples will undergo metabolomics and microbiome analysis to observe changes linked to the diet. The study will assess disease activity using markers such as C-reactive protein and fecal calprotectin. Throughout the study, patients will provide blood and stool samples before and after the diet intervention. Researchers will measure disease activity using the short Crohns Disease Activity Index after 42 days on the diet. The study involves regular monitoring of inflammation markers to evaluate how the Mediterranean Diet affects the disease state. Participants will be followed for the duration of the 42-day diet period to observe these changes.

Effect of Mediterranean Diet in Inflammatory Bowel Disease