Mediterranean Diet to Support Nutrition and Weight Management in Parkinsons Patients After Bilateral Subthalamic Nucleus Deep Brain Stimulation Surgery

What this Trial Is About

Researchers are investigating whether following a Mediterranean diet can help manage body weight and improve body composition in adults with Parkinsons disease who have undergone bilateral subthalamic nucleus deep brain stimulation STN DBS. The study aims to see if adhering to this diet for three months after surgery can control weight gain and positively affect clinical factors like nutritional status, appetite, quality of life, and physical activity compared to usual diet. Parkinsons disease involves motor and non-motor symptoms, and DBS is a surgical treatment for patients with motor fluctuations despite medication. Post-surgery weight gain is a concern due to changes in food intake and activity levels, which this study seeks to address through dietary guidance. Participants will be randomly assigned to either an intervention group receiving Mediterranean diet recommendations or a control group continuing their usual eating habits. The Mediterranean diet group will receive nutritional training focused on consuming olive oil as the main fat, plenty of vegetables, fruits, fish, legumes, and nuts, while limiting bakery products, sugary snacks, and red meat. These guidelines will be reinforced during monthly follow-ups over three months after DBS device activation. The control group will maintain their routine diet without specific instructions. During the study, participants will undergo evaluations before surgery and at one, two, and three months after surgery. Assessments include appetite scales, Parkinsons disease questionnaires, dietary adherence scales, food consumption records, and physical activity questionnaires. Investigators will also measure body weight, body composition, waist and neck circumference, arm circumference, and handgrip strength. The primary outcomes focus on changes in body weight, height, and body mass index over three months, with additional measures related to nutritional status, motor symptoms, diet, quality of life, and appetite being monitored throughout the study.

Effect of Mediterranean Diet on Nutrition in Parkinson's Disease Patients With Bilateral Subthalamic Deep Brain Stimulation