Actively Recruiting
Effect of Mediterranean vs Paleolithic Diet on RA Activity, Sarcopenia and QOL: 12-Week RCT
Led by Kasr El Aini Hospital · Updated on 2026-02-27
75
Participants Needed
1
Research Sites
25 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to evaluate the effects of Mediterranean and Paleolithic dietary interventions on nutritional status, disease activity, fatigue, sleep, and quality of life in adults with rheumatoid arthritis (RA). Participants aged 40-60 years will be randomly assigned to follow either a Mediterranean diet, a Paleolithic diet, or continue their usual diet for 12 weeks. The study will assess anthropometric measurements, disease activity score (DAS28), laboratory biomarkers (CBC, CRP, ESR, lipid profile, fasting glucose, HbA1c), and patient-reported outcomes. The trial will determine whether these diets improve RA management and overall well-being.
CONDITIONS
Official Title
Effect of Mediterranean vs Paleolithic Diet on RA Activity, Sarcopenia and QOL: 12-Week RCT
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 40 to 60 years
- Diagnosed with rheumatoid arthritis according to the 2010 ACR/EULAR criteria
You will not qualify if you...
- Having comorbidities such as diabetes mellitus, hypertension, gout, or thyroid dysfunction
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Kasr Al Ainy Hospital, Faculty of Medicine, Cairo University
Cairo, Al-Manial, Egypt, 11956
Actively Recruiting
Research Team
G
Gehad Maghraby, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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