Actively Recruiting
Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift
Led by University of Virginia · Updated on 2026-05-04
50
Participants Needed
1
Research Sites
317 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Anesthesiology residency requires extended and overnight shifts, which may negatively impact the quantity and quality of sleep. Previous studies have investigated the effect of night float shift work on anesthesiology resident sleep and performance and demonstrated that total sleep quantity and time spent in deep and rapid eye movement (REM) sleep were significantly reduced during night float and did not return to baseline after 3 nights of recovery. Melatonin is a hormone produced by the pineal gland, which regulates the circadian rhythm that governs sleep. Exogenous melatonin may be used as a sleep aid and is available over the counter in the United States. Melatonin is effective in realigning the circadian rhythm disorder caused by night shift work and increasing sleep duration; however, melatonin's effect on improving sleep in resident trainees has not been investigated. The investigators propose a prospective double-blinded randomized control trial to investigate the effect of melatonin on sleep quantity and quality in resident physicians assigned to a night float system.
CONDITIONS
Official Title
Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Post-Graduate Year 1-5
- Currently enrolled in anesthesiology, general surgery, obstetrics and gynecology, general medicine, or pediatrics residency at the University of Virginia
You will not qualify if you...
- Current use of sleep aids
- Diagnosed sleep disorder
- History of a pacemaker or other medical device
- Pregnant or breast-feeding females
- Bleeding disorders
- Depression
- High blood pressure
- Seizure disorders
- History of transplant on immunosuppression therapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Virginia
Charlottesville, Virginia, United States, 22908-0710
Actively Recruiting
Research Team
K
Keita Ikeda, PH.D.
CONTACT
E
Emily Chuang, MA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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