Actively Recruiting
Effect of Morus Nigra Mouthwash on Gingivitis Treatment
Led by Inonu University · Updated on 2026-04-13
30
Participants Needed
1
Research Sites
25 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this study is to evaluate the clinical, microbiological, and biochemical effects of Morus nigra (black mulberry) mouthwash when used as an adjunct to non-surgical periodontal treatment (scaling and root planing - SRP) in patients with generalized gingivitis. Participants will be randomly assigned to two groups: one receiving SRP only, and the other receiving SRP plus Morus nigra mouthwash twice daily for 14 days. Clinical parameters, cytokine levels in gingival crevicular fluid (TNF-alpha, IL-1beta, IL-10), and subgingival bacterial load will be assessed at baseline, 1 month, and 3 months.
CONDITIONS
Official Title
Effect of Morus Nigra Mouthwash on Gingivitis Treatment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of generalized gingivitis with Gingival Index greater than 1
- Presence of at least 20 natural teeth
- Systemically healthy individuals
- Ability to provide informed consent
You will not qualify if you...
- Smoking or use of tobacco products
- Presence of periodontitis with clinical attachment loss
- Use of antibiotics or anti-inflammatory drugs in the last 6 months
- Pregnancy or lactation
- History of allergy to Morus nigra or mouthwash components
- Systemic diseases such as diabetes or cardiovascular diseases
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Inonu University Faculty of Dentistry
Battalgazi, Malatya, Turkey (Türkiye), 44300
Actively Recruiting
Research Team
O
Omer Alperen Kırmızıgul, Assistant Professor
CONTACT
B
Burak Koçak, Dds
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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