Actively Recruiting

Age: 18Years +
All Genders
NCT06583252

Effect of Multimodal Monitoring Cluster Management on Patients with Severe Traumatic Brain Injury

Led by Xiangya Hospital of Central South University · Updated on 2024-09-03

200

Participants Needed

1

Research Sites

108 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Traumatic brain injury (TBI) is a serious global health problem, with about 27 million new cases each year. Severe head trauma can lead to intracranial hypertension and a range of complications such as cerebral edema and hypoxia of brain tissue. Intracranial pressure monitoring is key to modern TBI treatment, but this approach does not fully reflect all relevant pathophysiological changes. Multimodal monitoring allows for a more comprehensive assessment of the severity of TBI and guidance for individualized treatment to improve patient outcomes by integrating different monitoring methods. Although more research is needed to confirm its efficacy, multimodal monitoring has been recognized as an important clinical decision support tool in neuroscience intensive care. Future studies may further optimize this approach to monitoring and provide a more effective treatment strategy for patients with TBI.

CONDITIONS

Official Title

Effect of Multimodal Monitoring Cluster Management on Patients with Severe Traumatic Brain Injury

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age over 18 years
  • Diagnosis of an acute brain injury due to traumatic brain injury
  • Glasgow Coma Scale with no eye opening and a motor score of 5 or less at ICU admission or neuro-worsening within 48 hours with the same criteria
Not Eligible

You will not qualify if you...

  • History of a major stroke
  • Currently pregnant or likely to become pregnant
  • Decreased Glasgow Coma Scale score only due to intoxication, sedation, or extracranial injury as judged by the treatment team
  • Unlikely to comply with study procedures including follow-up, as judged by the investigator
  • Serious medical condition with life expectancy less than 6 months
  • Contraindications to MRI examination
  • Devastating traumatic brain injury progressing to brain death or no commitment to aggressive continuous treatment by medical team

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Xiangya Hospital

Changsha, Hunan, China, 410008

Actively Recruiting

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Research Team

Q

Qiaoling Tang

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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