Actively Recruiting
Effect of Multisite High-definition Transcranial Direct Current Stimulation Targeting Sensorimotor Network
Led by Chinese University of Hong Kong · Updated on 2024-10-18
30
Participants Needed
1
Research Sites
124 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Transcranial direct current stimulation (tDCS) has been applied to facilitate cortical excitability in stroke populations, as increasing evidence suggests that clinical recovery from stroke is attributed to neuroplastic reorganization. However, recovery from stroke following this kind of non-invasive neuromodulation remains divergent across stroke patients due to variations in their etiologies, lesion profiles and post-stroke duration. A novel multisite high definition tDCS (HD-tDCS) in healthy people showed that such network-targeted stimulation could enhance motor excitability beyond conventional stimulation which targeting only one region. The electrode placements could be determined by the montage optimization, which targets individual motor network activation navigated by task-based fMRI using computation algorithms. By targeting motor network, the new multisite electrode montage may provide a potential to facilitate better cortical activation than conventional tDCS montage.
CONDITIONS
Official Title
Effect of Multisite High-definition Transcranial Direct Current Stimulation Targeting Sensorimotor Network
Who Can Participate
Eligibility Criteria
You may qualify if you...
- First-ever stroke with stroke duration longer than 12 months
- Mild to moderate upper limb motor impairment with Fugl-Meyer Assessment scores between 15 and 53
- Ability to voluntarily perform hand grasping movements
- Adequate cognitive function to follow assessments and study instructions
You will not qualify if you...
- History of epilepsy or any condition that contraindicates brain stimulation or MRI scanning
- Severe joint contracture or pain in elbow or shoulder caused by neurological, neuromuscular, or orthopedic disorders
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Biomedical Engineering, The Chinese University of Hong Kong
Hong Kong, Hong Kong
Actively Recruiting
Research Team
R
Raymond Kai-yu Tong, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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