Actively Recruiting
Effect of Mutations in T2DM Susceptibility Genes on the Expression of Susceptibility Genes in Patients With T2DM and Controls
Led by The Affiliated Hospital of Xuzhou Medical University · Updated on 2024-02-28
300
Participants Needed
1
Research Sites
213 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In this study, investigators wanted to determine the effect of T2DM susceptibility gene mutations on self-expression. Participants (T2DM patients and controls) were recruited to identify genotypes and detect the levels of T2DM susceptibility genes expression in the fresh peripheral plasma. The normal pancreatic tissues or adjacent tissues of pancreatic cancer were also collected to identify the expression differences of T2DM susceptibility genes under different genotypes.
CONDITIONS
Official Title
Effect of Mutations in T2DM Susceptibility Genes on the Expression of Susceptibility Genes in Patients With T2DM and Controls
Who Can Participate
Eligibility Criteria
You may qualify if you...
- No drug therapy; aged 25 to 70 years; Hemoglobin A1c (HbA1c) 7%-12%; BMI 20-35 kg/m2; stable body weight (≤10% change within 3 months) for newly diagnosed T2DM patients
- Aged 25 to 60 years; BMI 19-26 kg/m2; in good health with no abnormalities in motor, digestive, respiratory, urogenital, blood, circulatory, nervous/mental, or endocrine systems for healthy subjects
- Aged 20 to 80 years; surgical resection of part or all of the pancreas; pancreatic lesions confirmed by enhanced CT, magnetic resonance, or pathology for surgical patients
You will not qualify if you...
- Prior use of antidiabetic drugs
- History of pancreatic surgery
- Severe organ damage
- Long-term use of drugs affecting pancreatic function
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
China, Jiangsu, Department of Endocrinology
Xuzhou, China, 221006
Actively Recruiting
Research Team
T
Tao Wang, Ph.D
CONTACT
X
Xiaoxing Yin, Ph.D
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here