Study of a New Vitamin B12 Formula on Physical and Mental Performance in Male Cyclists Aged 18 to 45

What this Trial Is About

Researchers are evaluating the effects of a new vitamin B12 formulation on both anaerobic and cognitive performance in trained male cyclists. The study aims to determine whether improved bioavailability of vitamin B12, leading to higher plasma levels, relates to enhanced physical and mental tasks. This randomized, double-blind, placebo-controlled, crossover trial involves healthy cyclists competing in junior and amateur categories who train between 6 and 15 hours per week. Participants are assigned to take either the new vitamin B12 supplement or a placebo for three days before testing and on the day of testing, three hours prior to performance assessments. Between each intervention, there is a seven-day washout period. The study includes three lab visits initial medical exam and blood draw, followed by two visits with standardized breakfast, Wingate test for anaerobic power, mental fatigue reaction tests, and blood draws for biochemical markers including vitamin B12 levels. During the study, participants undergo health evaluations including blood tests, electrocardiogram, body composition scans, and performance testing on a cycle ergometer. Researchers monitor physical and cognitive performance, biochemical markers, and sleep quality through questionnaires. Data is securely stored and the study spans approximately three weeks. The trial focuses on comparing the effects of the new vitamin B12 formulation versus placebo on these outcomes in trained cyclists aged 18 to 45 years.

Effect of a New Formulation of Vitamin B12 on Physical and Mental