Actively Recruiting
The Effect of Nicotinamide on the Clinical Outcome of Rheumatoid Arthritis Patients
Led by Ain Shams University · Updated on 2024-10-16
70
Participants Needed
1
Research Sites
78 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A randomized controlled interventional study to evaluate the efficacy and safety of nicotinamide supplementation in rheumatoid arthritis patients receiving conventional synthetic disease modifying anti-rheumatic drugs.
CONDITIONS
Official Title
The Effect of Nicotinamide on the Clinical Outcome of Rheumatoid Arthritis Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients (18-65 years).
- Patients with a diagnosis of established rheumatoid arthritis.
- Patients presenting with moderate to high disease activity identified as disease activity score-28 based on C-reactive protein levels (DAS-28-CRP) >3.2.
- Receiving stable regimen of one or more conventional disease modifying antirheumatic drugs for at least the past three months.
- Patients willing to sign an informed consent.
You will not qualify if you...
- Patients with a known history of hypersensitivity or drug allergies to nicotinamide.
- Patients receiving nicotinamide for any other indications.
- Receiving any dosage forms or dosage regimen of vitamin B3 supplementation.
- Receiving biologic disease modified antirheumatic drugs therapy.
- Impaired liver functions (liver transaminases level ≥ three times upper normal limits).
- Impaired kidney functions (estimated glomerular filtration rate (eGFR) < 30 ml/min).
- Pregnancy and lactation.
- Patients with other auto-immune diseases.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ain Shams University Hospitals
Cairo, Egypt
Actively Recruiting
Research Team
S
Sara A. Raslan, Bachelor
CONTACT
D
Dalia Abdelmohsen, Professor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here