Actively Recruiting
Effect of Nitropaste in Chest Masculinizing Surgery
Led by University of Virginia · Updated on 2024-06-06
256
Participants Needed
1
Research Sites
167 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Nitropaste is a topical agent that contains 2% nitroglycerin. It is an effective vascular smooth dilator, with more powerful effect on venous vasculature than arterial vasculature. While its main indication is for angina pectoris, there have been many studies showing improved survival of axial and random pattern flaps. Furthermore, recent clinical studies highlight significantly decreased mastectomy flap wound complication and need for sharp debridement. Nitropaste has low rates of side effects and is very well tolerated in general. To this date, there's no study that investigates its utility on patients who are undergoing chest masculinizing surgery. The purpose of this study is to investigate the potential utility of nitropaste in reducing rates of wound complications in patients undergoing chest masculinizing surgery.
CONDITIONS
Official Title
Effect of Nitropaste in Chest Masculinizing Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Any adult (18 or older) patients of any gender identity who are undergoing chest masculinizing surgery with double incision and free nipple grafting.
You will not qualify if you...
- Minor patients (younger than 18)
- Anyone who is not receiving free nipple grafting
- Anyone who is not using the double incision pattern
- Prisoners
- Anyone allergic to nitropaste
- Anyone taking phosphodiesterase inhibitors (e.g., Sildenafil, tadalafil, vardenafil)
- Anyone taking soluble guanylate cyclase stimulators (e.g., riociguat)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Virginia Medical Center
Charlottesville, Virginia, United States, 22902
Actively Recruiting
Research Team
R
Rachel H Park, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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