Actively Recruiting

Phase Not Applicable
Age: 18Years - 90Years
All Genders
NCT04957355

Effect of NMES on Balance and Fall Risk in Chronic Stroke

Led by University of Illinois at Chicago · Updated on 2024-11-27

20

Participants Needed

1

Research Sites

237 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this study is to describe the effect of neuromuscular electrical stimulation (NMES) in the form of functional electrical stimulation (FES) applied to different lower limb muscles on reactive balance and gait performance in stroke participants. Methods: Twenty individuals with chronic stroke will be asked to perform an experimental protocol that includes a postural disturbance in the form of a slip- or trip-like perturbation and a standardized walking test in both laboratory and outdoor environments with and without FES applied to different lower limb muscles of the paretic leg. FES will be applied using an advanced software that is able to synchronize muscle activation with the time of perturbation onset and according to the phases of gait. This project design aims to examine whether a specific pattern of lower limb muscle stimulation could improve the kinematic and behavioral responses during reactive balance following slip- and trip-like perturbations. Additionally, the project aims to see if the kinematic and spatio-temporal gait parameters can be modified during a standardized walking test under different sensory and environmental conditions.

CONDITIONS

Official Title

Effect of NMES on Balance and Fall Risk in Chronic Stroke

Who Can Participate

Age: 18Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 90 years
  • Presence of hemiparesis
  • Stroke occurred more than 6 months ago
  • Ability to walk independently with or without assistive device for at least 300 feet
  • Ability to understand and communicate in English
  • Cognitively and behaviorally able to follow study procedures (Montreal Cognitive Assessment score above 25/30)
Not Eligible

You will not qualify if you...

  • Heart rate above 85% of age-predicted maximum at rest
  • Systolic blood pressure over 165 mmHg or diastolic blood pressure over 110 mmHg at rest
  • Oxygen saturation below 95% at rest
  • Body weight over 250 pounds
  • Any neurological condition other than stroke
  • Any cardiopulmonary, musculoskeletal, or systemic illness
  • Recent major surgery within last 6 months or hospitalization within last 3 months
  • History of deep venous thrombosis
  • History of cancer
  • Peripheral nerve injury or neuropathy causing motor disability in affected limb
  • Muscle spasticity above Ashworth scale level 2
  • Uncontrolled high blood pressure or angina
  • Skin conditions that do not tolerate FES therapy
  • Uncontrolled seizure disorder
  • Botox treatment within last 5 months
  • History of epilepsy
  • Use of a pacemaker
  • Non-English speakers are excluded due to consent and instruction language requirements

AI-Screening

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Trial Site Locations

Total: 1 location

1

University of Illinois at Chicago

Chicago, Illinois, United States, 60612

Actively Recruiting

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Research Team

R

Rudri M Purohit, MS,PT

CONTACT

L

Lakshmi Kannan, MS,PT

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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