Actively Recruiting
Effect of Omega-3 Fatty Acid Supplementation on Dry-AMD Progression
Led by Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine · Updated on 2026-01-02
24
Participants Needed
1
Research Sites
28 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This randomized, double-blind, placebo-controlled study aims to evaluate the effect of krill oil supplementation in patients with dry age-related macular degeneration (AMD). Participants will receive 4 capsules of krill oil or placebo daily for a period of 3 months. Outcomes will be evaluated after 3-month treatment to assess differences between the two study groups.
CONDITIONS
Official Title
Effect of Omega-3 Fatty Acid Supplementation on Dry-AMD Progression
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults diagnosed with early or intermediate dry AMD according to Beckman Classification confirmed by fundus photography
- Willing to stop taking omega-3 fatty acids, choline, or astaxanthin supplements
- Willing to sign informed consent and attend follow-up visits for at least 3 months
You will not qualify if you...
- Any eye disease interfering with fundus examinations
- Eye conditions including choroidal neovascularization, geographic atrophy, or high myopia
- Eye surgeries that affect AMD evaluation
- Long-term use of medications with retinal or neural toxicities
- Recent supplementation with lutein, zeaxanthin, DHA, or EPA without an 8-week washout
- Intraocular pressure above 26 mmHg
- Cataract surgery within the past 3 months
- Severe systemic diseases or conditions causing high risk of drop-out or low compliance
- Participation in other trials interfering with this study
- Use of angiogenesis inhibitor drugs for cancer treatment
- Any other condition unsuitable for this study
AI-Screening
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Trial Site Locations
Total: 1 location
1
Shanghai General Hospital, Shanghai Jiao Tong University
Shanghai, China, 200080
Actively Recruiting
Research Team
H
Huixun Jia, PhD
CONTACT
J
Jiayu Xu
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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