Actively Recruiting
The Effect of Oral Iron Supplements on Insulin and Glucose Metabolism in Overweight and Obese Women
Led by Nicole Stoffel · Updated on 2026-01-02
70
Participants Needed
1
Research Sites
27 weeks
Total Duration
On this page
Sponsors
N
Nicole Stoffel
Lead Sponsor
A
American University of Beirut Medical Center
Collaborating Sponsor
AI-Summary
What this Trial Is About
The study will be a randomized, double-blind, 17-day metabolic intervention trial including 14 days of high-dose or low-dose iron supplementation. A total of 70 overweight or obese (OW/OB) women will be enrolled. Participants will be individually randomized into either the high-iron or low-iron group. Women in the low-iron group will receive 15 mg of iron as ferrous fumarate daily for 14 days, while women in the high-iron group will receive 195 mg of iron as ferrous sulfate daily for 14 days. The study consists of three visits in total. On Day 0, a fasting blood sample will be collected and an OGTT will be performed, with additional blood samples collected at 1 hour and 2 hours post-OGTT. The OGTT will be repeated on Day 14, after 14 days of oral iron supplementation, and again on Day 17, four days after oral iron supplementation has been stopped
CONDITIONS
Official Title
The Effect of Oral Iron Supplements on Insulin and Glucose Metabolism in Overweight and Obese Women
Who Can Participate
Eligibility Criteria
You may qualify if you...
- BMI 65 27.5 kg/m2
- Serum ferritin less than 30 bcg/L
- Hemoglobin of 11 g/dl or higher
- Fasting blood glucose below 5.6 mmol/L
You will not qualify if you...
- Received intravenous or high dose oral iron in the preceding 2 months
- Medical disorders affecting iron absorption, metabolism, or type 2 diabetes mellitus
- Cigarette smoking
- Recent blood transfusion or major blood loss
AI-Screening
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Trial Site Locations
Total: 1 location
1
American University of Beirut
Beirut, Lebanon
Actively Recruiting
Research Team
O
Omar Obeid
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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