Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06753305

The Effect of Ozone Therapy on Gingivoplasty

Led by Kutahya Health Sciences University · Updated on 2025-09-05

48

Participants Needed

1

Research Sites

178 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Ozone therapy after gingivectomy and gingivoplasty has been found to reduce patients' pain levels and positively impact their quality of life. This study aimed to compare the healing potential of the wound surface following gingivectomy and gingivoplasty surgery applied to the maxillary anterior regions with classical periodontal paste application (Coe-pak) using activated oxygen (Cure 09 Active Oxygen) and classical periodontal paste application only (Coe-pak). The study will include 48 systemically healthy patients older than 18 years of age with gingival enlargement in the maxillary anterior region, requiring gingivectomy and gingivoplasty surgery, who applied to Kütahya University of Health Sciences, Faculty of Dentistry, Department of Periodontology and Izmir Democracy University, Faculty of Dentistry, Department of Periodontology. Patients will be evaluated in two different groups as test and control group after surgery. Patients will be randomly divided into study groups by closed envelope method. The test group will receive periodontal paste (Coe-pak) + Ozone therapy (active oxygen (Cure 09 Active Oxygen)) after gingivectomy and gingivoplasty surgery, while the control group will receive only periodontal paste after gingivectomy and gingivoplasty surgery. All patients will undergo gingivectomy and gingivoplasty with the same procedure

CONDITIONS

Official Title

The Effect of Ozone Therapy on Gingivoplasty

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Be over 18 years old
  • Be systemically healthy
  • Have gingival enlargement due to inflammation in at least 4 teeth in the upper front (maxillary anterior) region
  • Have a horizontal and vertical gingival growth index score of 1 or 2
  • Have gingival thickness more than 2 mm
  • Have good oral hygiene
  • Have no loss of clinical attachment
Not Eligible

You will not qualify if you...

  • Currently pregnant
  • Have hereditary gingival fibromatosis
  • Have drug-induced gingival enlargement
  • Have any allergies
  • Have systemic conditions requiring antibiotic prophylaxis
  • Have acute and untreated periodontitis

AI-Screening

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Trial Site Locations

Total: 1 location

1

Kütahya Health Sciences University Faculty of Dentistry

Kütahya, Turkey (Türkiye), 43100

Actively Recruiting

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Research Team

B

Berceste Güler Ayyıldız

CONTACT

S

Seyma Eken

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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