Evaluating Paracervical Block for Reducing Pain After vNOTES Uterosacral Ligament Suspension Surgery in Women

What this Trial Is About

Researchers are evaluating the effect of paracervical block on early postoperative pain after vaginal natural orifice transluminal endoscopic surgery vNOTES uterosacral ligament suspension in female patients with pelvic organ prolapse. This prospective, randomized, double-blind, placebo-controlled trial aims to determine whether paracervical block with local anesthetic reduces pain in the early recovery period following this minimally invasive gynecologic surgery. Participants will be randomly assigned to receive either 10 mL of 0.5% bupivacaine or 10 mL of normal saline as a paracervical injection during the vNOTES uterosacral ligament suspension procedure. The study uses computer-generated randomization with allocation concealment, and the solutions are prepared in identical syringes to maintain blinding. Treatment is given during surgery, and participants are followed postoperatively. During the study, postoperative pain will be assessed using the Visual Analog Scale VAS at several time points up to 24 hours after surgery, with the primary outcome measured at 6 hours. Secondary measures include total pain scores within 24 hours, analgesic use, hospital stay length, and patient satisfaction. The trial monitors recovery and pain management closely to evaluate if paracervical block offers meaningful pain relief.

Effect of Paracervical Block on Postoperative Pain After vNOTES Uterosacral Ligament Suspension