Actively Recruiting
Effect of Pentoxifylline + CoQ10 vs CoQ10 Alone on Sperm Motility in Subfertile Men With Asthenozoospermia
Led by Mst.Sumyara Khatun · Updated on 2025-11-26
56
Participants Needed
1
Research Sites
73 weeks
Total Duration
On this page
Sponsors
M
Mst.Sumyara Khatun
Lead Sponsor
B
Bangladesh Medical University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if drug Pentoxifylline plus Coenzyme Q10 work to treat asthenozoospermia in subfertile male. It will also learn about the safety of drug Pentoxifylline plus Coenzyme Q10. The main questions it aims to answer are: Does drug Pentoxifylline plus Coenzyme Q10 increase the motility of sperm in participants? What medical problems do participants have when taking drug Pentoxifylline plus Coenzyme Q10 ? Researchers will compare drug Pentoxifylline plus Coenzyme Q10 combination to Coenzyme Q10 alone to see if drug Pentoxifylline plus Coenzyme Q10 combination works better. Participants will: Experimental Group:Pentoxifylline 400mg twice dailyand Coenzyme Q10 100mg twice daily for 3 months. Comparator Group: Coenzyme Q10 100mg twice daily for 3 months Visit the clinic after three months of treatment for checkups and tests
CONDITIONS
Official Title
Effect of Pentoxifylline + CoQ10 vs CoQ10 Alone on Sperm Motility in Subfertile Men With Asthenozoospermia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subfertile men with asthenozoospermia (total motility 20% to less than 42%) according to WHO semen analysis, 2021
- Age between 20 and 50 years
You will not qualify if you...
- Severe oligoasthenoteratozoospermia
- Any medical, endocrine, or genetic disorders
- History of chemotherapy or radiotherapy
- Genital infection or genital surgery
- Antioxidant supplementation in the last 3 months
- Drug, alcohol, or substance abuse
- Psycho-sexual abnormalities
- Known hypersensitivity to xanthine-related products
- Recent cerebral or retinal hemorrhage
AI-Screening
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Trial Site Locations
Total: 1 location
1
Bangladesh Medical University
Dhaka, Shahbag, Bangladesh, 1000
Actively Recruiting
Research Team
M
Mst.Sumyara Khatun, MS
CONTACT
K
Kazi Jannatul Ferdouse, MBBS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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