Actively Recruiting
Effect of Percussive Massage on Skeletal Muscle During Limb Immobilization
Led by Brigham Young University · Updated on 2024-08-13
36
Participants Needed
1
Research Sites
126 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary aims of this study are to determine the effect of percussive massage (30 min/session, 2 sessions/day, daily) during 10 days of unilateral limb immobilization on preserving muscle, vascular, and mitochondrial function. The following hypotheses will be tested: Hypothesis 1: Percussive massage will attenuate the loss of size, strength and endurance over the immobilization period compared to the control group, as measured by MRI, maximal isometric and isokinetic force production and muscle endurance test using Biodex dynamometry. Hypothesis 2: Percussive massage will attenuate the loss of vascular function and blood flow compared to the control group as measured by passive leg movement and femoral artery blood flow. Hypothesis 3: Percussive massage will attenuate the loss of skeletal muscle mitochondrial function and decrease H2O2 production during immobilization compared to the control group, as measured by high-resolution respirometry.
CONDITIONS
Official Title
Effect of Percussive Massage on Skeletal Muscle During Limb Immobilization
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 50 years, women must be pre-menopausal
- Stable physical activity levels for at least 6 months
- No previous lower leg injury preventing knee extension exercises
You will not qualify if you...
- Current cigarette or marijuana smoker
- Pregnant or planning pregnancy within one month
- Diagnosed cardiovascular, metabolic, or cognitive diseases
- Taking prescribed medications or anti-depressants
- Regular use of massage or vibration on the thigh
- Unable to understand and provide informed consent
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Brigham Young University
Provo, Utah, United States, 84602
Actively Recruiting
Research Team
R
Robert D Hyldahl, PhD
CONTACT
T
Ty Hopkins, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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