Actively Recruiting
Effect on Periodontal Phenotype of Flapless Piezoincission During Orthodontic Treatment
Led by Universidad Complutense de Madrid · Updated on 2026-05-08
40
Participants Needed
1
Research Sites
136 weeks
Total Duration
On this page
Sponsors
U
Universidad Complutense de Madrid
Lead Sponsor
O
Osteology Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
Research Question While the reduction in treatment times and the patient satisfaction after periodontally accelerated osteogenic orthodontics (PAOO) are well sustained in the scientific literature, there is still controversy regarding if grafting leads to i) change of the periodontal phenotype and ii) greater stability of post-orthodontic treatment outcomes, highlighting the need of controlled clinical trials. Aims of the Project The aim of this randomized clinical trial (RCT) is to compare piezocision-assisted orthodontics, concomitant to soft tissue grafting (volume-stable collagen matrix), with piezocision-assisted orthodontics, concomitant to bone grafting with a xenograft and a native collagen membrane, in orthodontic non-growing patients. The primary aim will be to determine the impact of this surgical protocol on the hard and soft tissue changes occurring on the buccal aspect of the dentition. Secondary objectives will include the assessment of the comparative impact on treatment duration, rate of tooth movements, presence of root resorption, periodontal parameters, bone level changes and patient-reported outcome measures (PROMs) between the two groups.
CONDITIONS
Official Title
Effect on Periodontal Phenotype of Flapless Piezoincission During Orthodontic Treatment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients requiring maxillary and/or mandible orthodontic treatment
- Patients with permanent dentition in stage 5 or 6 of cervical vertebral maturation
- Minimal to moderate maxillary and/or mandibular anterior crowding (3-8 mm arch length discrepancy)
- Adequate oral health with no periodontal disease, periapical infections, or untreated caries
You will not qualify if you...
- Subjects with stage III or IV periodontitis
- Subjects with poor oral hygiene (full-mouth plaque scores over 25%)
- Ongoing chronic drug therapy affecting bone metabolism (e.g., steroids, immunosuppressors, antiresorptive drugs)
- Subjects with uncontrolled systemic diseases such as diabetes
- Pregnancy
- Subjects unwilling to comply with study visits
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Faculty of Odontology, University Complutense Madrid
Madrid, Spain, 28040
Actively Recruiting
Research Team
E
Eduardo Montero, Prof
CONTACT
C
Conchita Martin, Prof
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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