Study of Photobiomodulation to Reduce Pain and Improve Healing After Endodontic Microsurgery with Vertical Releasing Incisions

What this Trial Is About

Researchers are evaluating the impact of Photobiomodulation PBM therapy on postoperative pain and healing after endodontic microsurgery EMS in adults. The study focuses on patients undergoing EMS with vertical releasing incisions VRI and aims to assess how PBM affects pain relief and soft tissue healing. This study is conducted by the University of Texas Health Science Center at Houston and explores a promising light-based therapy that stimulates cellular activity to improve healing and reduce inflammation. Forty adult patients will be divided into two groups one receiving conventional EMS plus PBM treatment using a 660 nm diode laser applied to the incision area, and the other receiving conventional EMS plus a sham PBM treatment without laser activation. EMS procedures involve anesthesia, microscopic surgical techniques, root-end resection, and suturing. PBM therapy is applied immediately after surgery by irradiating the incision site for 25 seconds at a specific energy density. The control group undergoes the same EMS but with sham laser treatment. Participants will have pain levels measured by a visual analog scale before surgery, on the day of surgery, and 5 to 7 days after surgery at suture removal. Healing will be evaluated using the Early Wound Healing Score at baseline, immediately post-surgery, and during suture removal. Photos and visual inspections will track soft tissue recovery. The entire study monitors postoperative pain and tissue healing to understand PBMs effects after EMS, with participation lasting through the suture removal period about a week later.

Effect of Photobiomodulation on Pain and Healing of the Vertical Releasing Incision After Endodontic Microsurgery