Actively Recruiting
Effect of Physical Training in Individuals With Hypokalemic and Hyperkalemic Periodic Paralysis
Led by Rigshospitalet, Denmark · Updated on 2026-03-30
36
Participants Needed
1
Research Sites
60 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study wishes to investigate the effects of strength exercise in patients with either HypoPP or HyperPP. The investigators wishes to include participants already diagnosed with either HypoPP or HyperPP in af 24 week prospective study where the patients will be tested and asked to fill out questionnaires three times. These appointments will be schedueled at week 0, week 12 and week 24. In the time period between week 12 and week 24, the patients will have a personalized strength exercise program, which they will have to follow these 3 months. The exercise will be supervised by one or more of the investigators. We will also assess the muscle structure and function cross sectionally.
CONDITIONS
Official Title
Effect of Physical Training in Individuals With Hypokalemic and Hyperkalemic Periodic Paralysis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with genetically verified Hypokalemic Periodic Paralysis or Hyperkalemic Periodic Paralysis
- Age 18 years or older
- Able to walk at least 10 meters independently with or without assistive devices
- Able to stand from a chair without using hands
You will not qualify if you...
- Presence of another significant cause of muscle weakness
- Heart or lung disease that makes participation in study training inadvisable according to the investigator
- Receiving anticoagulant treatment or having impaired blood clotting preventing muscle biopsy
- Metal implants that prevent MRI scanning or affect scan quality
- Claustrophobia
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Rigshospitalet, Copenhagen Neuromuscular Center
Copenhagen, Denmark, 2100
Actively Recruiting
Research Team
A
Annica B Enegaard
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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