Comparing Point-of-Care and Laboratory Ultrasensitive Troponin I Testing to Reduce Hospital Stay Length in Patients With Chest Pain

What this Trial Is About

Researchers are comparing two methods for measuring high-sensitivity troponin I, a key marker used to diagnose heart attacks, in patients arriving at the emergency room with chest pain symptoms suggestive of Acute Coronary Syndrome ACS. The study aims to find out if using the Atellica VTLi kit from Siemens for point-of-care testing can reduce the time from hospital admission to discharge compared to the traditional laboratory method using the Alinity i kit from ABBOTT. This randomized, open, parallel study involves 200 patients and is conducted at a single center. Participants will be randomly assigned to one of two groups. The point-of-care group will have whole capillary blood collected by fingertip puncture and tested rapidly using the Siemens Atellica VTLi kit, which provides results in about 8 minutes. The control group will have blood drawn by venipuncture and tested with the ABBOTT Alinity i kit in the laboratory. Both groups will have samples taken at admission and one hour later. The study compares speed, accuracy, and cost-effectiveness of these two diagnostic methods. During the study, participants will have blood samples collected and undergo serial troponin testing. Researchers will measure the time from hospital admission to discharge after diagnosis of Non-ST Elevation Acute Coronary Syndrome NSTE-ACS. They will also assess differences in troponin levels, timing of diagnosis, result turnaround time, hospital discharge times for ruled-out cases, major adverse cardiovascular events, and cost-effectiveness over 30 days. The study involves informed consent and continuous monitoring during hospital stay and follow-up periods.

Effect of Point-of-care Analysis of Ultrasensitive Troponin I on Length of Hospital Stay in Patients With Cardiac Chest Pain (POC Troponina)