Actively Recruiting

Phase Not Applicable
Age: 1Month - 2Months
All Genders
ID07579013

Immediate Effects of Postural Drainage With or Without Thoracic Squeezing on Oxygen Saturation and Respiratory Rate in Children With Respiratory Distress Syndrome

Led by Riphah International University · Updated on 2026-05-11

14

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating whether adding thoracic squeezing to postural drainage can improve immediate respiratory outcomes in preterm infants with Respiratory Distress Syndrome (RDS). This study involves preterm infants born via cesarean section and aims to compare the effects of postural drainage alone versus postural drainage combined with the lung squeezing technique (LST) on oxygen levels and respiratory distress. The study randomly assigned 14 preterm infants into two groups over nine months. The control group received standard care with postural drainage, while the experimental group received postural drainage combined with gentle chest pressure (LST) to help move mucus and improve airflow. Postural drainage sessions last 4-5 minutes and repeat every 3 hours, while thoracic squeezing is performed for about 10 minutes on each side after drainage. Continuous monitoring is done to ensure safety during treatments. Participants are monitored using the Oxygen Saturation Index to measure oxygen levels and the Silverman-Anderson Scale to assess respiratory distress at baseline and after 4 weeks. The study includes assessments of vital signs and respiratory status. Data are analyzed to determine if combining thoracic squeezing with postural drainage improves oxygenation and reduces respiratory effort more than postural drainage alone. The total participation period covers baseline and a 4-week follow-up.

CONDITIONS

Brief Title

Effect of Postural Drainage With or Without Thoracic Squeezing on O2 and Respiratory Rate in Infant With RDS.

Who Can Participate

Age: 1Month - 2Months
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children diagnosed with Respiratory Distress Syndrome (RDS)
  • Preterm infants born by cesarean section
  • No congenital malformations
Not Eligible

You will not qualify if you...

  • Currently under treatment with neurotropic drugs
  • Respiratory or cardiac congenital anomalies
  • Genetic disorders
  • Interventricular hemorrhage or seizures

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 4 weeks

Participants receive chest physiotherapy sessions including postural drainage with or without thoracic squeezing to improve oxygen saturation and respiratory rate.

Repeated sessions every 3 hours during hospitalization over the 4-week period

Trial Site Locations

Total: 1 location

1

Children Hospital

Lahore, Punjab Province, Pakistan, 54000

Actively Recruiting

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Research Team

I

IMRAN AMJAD, PHD

M

MUHAMMAD ASIF JAVED, PhD*

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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