Trait covariance: the functional warp of plant diversity?
Anthony P Walker, M Luke McCormack, Julie Messier...
https://pubmed.ncbi.nlm.nih.gov/29110312Actively Recruiting
Led by Aysenur Dostbil · Updated on 2026-04-01
150
Participants Needed
1
Research Sites
N/A
Total Duration
Spinal anesthesia-induced hypotension is a common and significant complication affecting up to 50-80% of pregnant women undergoing elective cesarean section. This trial evaluates whether a brief 5-minute mindfulness-based breathing exercise given just before spinal anesthesia can influence blood pressure changes during surgery. The study compares this breathing technique to standard care in pregnant women aged 18 to 45 years scheduled for elective cesarean delivery. Participants will be randomly assigned to either perform the mindfulness-based breathing exercise or receive standard preoperative care. The breathing exercise involves slow diaphragmatic breathing at about six breaths per minute, guided by a trained anesthesiologist or nurse, with mindful repetition of the phrase "My body is relaxing as I exhale." Both groups receive spinal anesthesia with specific medications, and careful monitoring of heart rate and blood pressure is performed. During the study, participants will be closely observed for changes in systolic blood pressure and heart rate within 10 minutes after spinal anesthesia. Anxiety levels, incidence of early hypotension, and medication use to support blood pressure will also be measured. The trial includes standard monitoring such as ECG and oxygen saturation, with safety and response data collected throughout the procedure. Participants' involvement includes a short breathing exercise or equivalent wait time before anesthesia, with follow-up assessments during surgery.
CONDITIONS
"Effect of Pre-Spinal Mindfulness-Based Breathing Exercise on Hemodynamic Response in Elective Cesarean Section"
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants receive either a 5-minute mindfulness-based breathing exercise immediately before spinal anesthesia or standard preoperative care without breathing exercises. All participants undergo spinal anesthesia for elective cesarean section.
1 visit in the operating room
Duration - Up to 10 minutes following spinal anesthesia induction
Participants are monitored for hemodynamic responses and safety outcomes up to 10 minutes after spinal anesthesia induction, including blood pressure and heart rate changes.
Monitoring during the surgery visit
Total: 1 location
1
Atatürk University Research Hospital
Erzurum, Turkey (Türkiye), 25240
Actively Recruiting
E
esra dilara ayber, MD
A
aysenur dostbil, PROF. DR.
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
Have more questions? Get in touch with our team for quick support
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Anthony P Walker, M Luke McCormack, Julie Messier...
https://pubmed.ncbi.nlm.nih.gov/29110312Anderson G Teixeira, Aldacilene S Silva, Fabio L H Lin...
https://pubmed.ncbi.nlm.nih.gov/20626361Marc A Russo, Danielle M Santarelli, Dean O'Rourke
https://pubmed.ncbi.nlm.nih.gov/29209423Fred Shaffer, J P Ginsberg
https://pubmed.ncbi.nlm.nih.gov/29034226