Actively Recruiting
Effect of Prebiotic Sodas on Postprandial Levels of GLP-1, PYY, Transit Time and Satiety Levels: A Pilot Study
Led by Olipop, PBC · Updated on 2026-01-28
15
Participants Needed
1
Research Sites
17 weeks
Total Duration
On this page
Sponsors
O
Olipop, PBC
Lead Sponsor
I
INQUIS Clinical Research
Collaborating Sponsor
AI-Summary
What this Trial Is About
The main objective of this study is to evaluate the acute effects of prebiotic sodas on postprandial levels of glucagon-like peptide-1 (GLP-1), peptide YY (PYY), gastric emptying, and satiety levels in healthy adults.
CONDITIONS
Official Title
Effect of Prebiotic Sodas on Postprandial Levels of GLP-1, PYY, Transit Time and Satiety Levels: A Pilot Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18-60 years, inclusive.
- Body mass index (BMI) between 18.0 and 30.0 kg/m2.
- Stable weight in the last 3 months (within +/-5 kg).
- Willing to avoid unusual strenuous exercise, alcohol, and fiber supplements for 24 hours before study days.
- Willing to refrain from smoking tobacco or e-cigarettes and marijuana use for 12 hours before and during study visits.
- Able to understand study procedures and provide informed consent and authorization for protected health information release.
- Eligible to receive income in Canada and covered by a health insurance plan such as Ontario Health Insurance Plan (OHIP).
You will not qualify if you...
- Pregnant or breastfeeding women.
- History of severe food allergies or allergy to acetaminophen.
- Known diabetes, gastrointestinal disorders affecting nutrient absorption, liver disease, or other health conditions that increase risk or affect results as judged by the investigator.
- Use of oral or injectable GLP-1 receptor agonist medications currently or within the last 2 months.
- Consumption of more than 14 alcoholic drinks per week or more than 5 drinks on any occasion.
- Antibiotic therapy within the last 2 months.
- Use of blood thinning drug warfarin.
- Habitual use of supplements such as berberine, curcumin, cinnamon, resveratrol, or gardenia in the past 30 days.
- Major surgery within the last 3 months.
- Unwillingness or inability to comply with study procedures and safety guidelines.
- Current or recent (within 30 days) participation in a clinical trial involving long-term exposure to investigational drugs, supplements, or lifestyle changes.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Inquis Clinical Research
Toronto, Ontario, Canada, M5C 2N8
Actively Recruiting
Research Team
D
Director of Clinical Operations
CONTACT
S
Senior Scientist
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
4
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