Study of Local Anesthetic Injection to Reduce Pain Before Vaginal Incision in Hysterectomy by vNOTES Surgery

What this Trial Is About

This research evaluates the effect of preventive pain relief by injecting a local anesthetic called Ropivacaine before making a vaginal incision during a hysterectomy using the vNOTES approach. The study focuses on adult female patients aged 18 to 70 undergoing this surgery for benign conditions. The trial is randomized and double-blind, comparing Ropivacaine injection to a saline placebo to assess pain after surgery. Participants will be randomly assigned to one of two groups before surgery one group receives 20 mL of Ropivacaine injected as a paracervical block at four points, 3 mm deep into the vaginal cul-de-sac, three minutes before the vaginal incision, while the other group receives 20 mL of saline placebo. Both groups will have general anesthesia and receive the same standard pain relief during and after surgery. During the study, researchers will measure pain levels four hours after surgery using questionnaires including numerical rating scales and others related to sexual function and quality of life. Participants will be monitored for safety and treatment effects with consistent postoperative care. The overall participation will last through the surgery and immediate recovery, with pain assessment as the main outcome measure.

Effect of Preventive Analgesia by Injection of a Local Anesthetic Before Vaginal Incision for Hysterectomy by vNOTES Approach