Actively Recruiting
Effect of Probiotic Intervention on Travel-Related Health Conditions During Short-Term Overseas Travel
Led by Universiti Sains Malaysia · Updated on 2025-09-17
46
Participants Needed
2
Research Sites
21 weeks
Total Duration
On this page
Sponsors
U
Universiti Sains Malaysia
Lead Sponsor
T
Tsinghua University Science and Technology
Collaborating Sponsor
AI-Summary
What this Trial Is About
International travel disrupts gut health through dietary changes, microbial exposure, and stress, often causing gastrointestinal symptoms like traveler's diarrhea and sleep disturbances. These shifts may increase antibiotic resistance risks. Probiotics may help stabilize gut microbiota and improve well-being during travel. This randomized, double-blind, placebo-controlled trial investigated whether probiotic supplementation mitigates gut microbiota perturbations, gastrointestinal symptoms, and sleep issues in adults traveling abroad. The investigators also assessed changes in anxiety, well-being, gut immunity, microbial function, and antibiotic resistance genes.
CONDITIONS
Official Title
Effect of Probiotic Intervention on Travel-Related Health Conditions During Short-Term Overseas Travel
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Generally healthy adults
- Scheduled to undertake a short-term round trip (less than 7 days) abroad
- Able to complete study procedures
- Willing to take intervention products
You will not qualify if you...
- Use of antibiotics, probiotics, hormones, immunosuppressants, biologics, or JAK inhibitors within four weeks prior to study
- Chronic or severe systemic diseases including cardiovascular, hepatic, renal, malignant, or psychiatric disorders
- Uncontrolled parasitic infections
- Long-term use of corticosteroids, growth hormone, vitamin B12, lysine, or inositol
- Major surgery within one month
- Allergy to probiotic components
- Other conditions deemed inappropriate by investigators
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Tsinghua University Science and Technology
Haidian, Beijing Municipality, China, 100080
Actively Recruiting
2
Universiti Sains Malaysia
George Town, Pulau Pinang, Malaysia, 11800
Not Yet Recruiting
Research Team
M
Min Tze Liong, Ph.D.
CONTACT
Y
Yuan Jie, M.Sc.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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