Actively Recruiting
: EFFECT OF PROBIOTIC SUPPLEMENTATION ON ATYPICAL ANTIPSYCHOTIC INDUCED WEIGHT GAIN IN PATIENTS ATTENDING PSYCHIATRIC CLINICS AT AINSHAMS UNIVERSITY HOSPITALS (A RANDOMIZED CONTROLLED TRIAL)
Led by Ain Shams University · Updated on 2025-04-20
180
Participants Needed
1
Research Sites
87 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
the goal of the study is to improve the quality of life of patients on antipsychotic medications and increase the rate of compliance to treatment. Primary objective: 1.To determine the effectiveness of probiotics to decrease the weight gained as a result of antipsychotic medications. Secondary objective: 1\. To determine the effect of probiotic supplementation on the psychological state of patients.
CONDITIONS
Official Title
: EFFECT OF PROBIOTIC SUPPLEMENTATION ON ATYPICAL ANTIPSYCHOTIC INDUCED WEIGHT GAIN IN PATIENTS ATTENDING PSYCHIATRIC CLINICS AT AINSHAMS UNIVERSITY HOSPITALS (A RANDOMIZED CONTROLLED TRIAL)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult schizophrenia patients aged 18 to 45 years
- Patients on second generation antipsychotics
- Stable patients with a total PANSS score of 60 or less
- More than 10% weight gain after taking atypical antipsychotics for at least 3 months
- Treatment duration not more than two years
You will not qualify if you...
- Taking probiotics, fiber supplements, antibiotics, or laxatives in the last 6 weeks
- Comorbid gastrointestinal diseases including active peptic ulcer, uncontrolled and recurrent diarrhea, gastrointestinal bleeding, and digestive system cancers
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
AinShams university hospitals
Cairo, Abbassia, Egypt, 00202
Actively Recruiting
Research Team
R
Rehab Abdelmaksoud
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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