Effect of Probiotic Supplementation on Weight Gain Caused by Atypical Antipsychotics in Adults With Schizophrenia at Ain Shams University Hospitals

What this Trial Is About

Researchers are evaluating the effects of probiotic supplementation on weight gain caused by atypical antipsychotic medications in adult patients attending psychiatric clinics. The study aims to improve the quality of life by reducing weight gain and increasing treatment compliance among patients taking these medications. It also examines the impact of probiotics on patients psychological state. Participants will be randomly assigned to receive either a probiotic supplement called Lacteol fort 10 billion, which contains lactobacillus LS and a culture medium, or no additional intervention while continuing their standard antipsychotic treatment. The study will last 12 weeks, focusing on changes in weight and psychological assessments. During the study, patients weight and psychological status will be monitored regularly. Researchers will assess the effectiveness of probiotics in decreasing weight gain associated with antipsychotic use. The main outcome will be measured after 12 weeks of treatment. Participants will be followed to ensure adherence and safety throughout the trial period.

: EFFECT OF PROBIOTIC SUPPLEMENTATION ON ATYPICAL ANTIPSYCHOTIC INDUCED WEIGHT GAIN IN PATIENTS ATTENDING PSYCHIATRIC CLINICS AT AINSHAMS UNIVERSITY HOSPITALS (A RANDOMIZED CONTROLLED TRIAL)