Actively Recruiting

Phase Not Applicable
Age: 1Day - 90Days
All Genders
Healthy Volunteers
NCT05524649

Effect of Probiotics on Infant's Fecal Microbiota Composition

Led by AB Biotics, SA · Updated on 2025-02-11

120

Participants Needed

2

Research Sites

187 weeks

Total Duration

On this page

Sponsors

A

AB Biotics, SA

Lead Sponsor

M

Ministry of Science and Innovation, Spain

Collaborating Sponsor

AI-Summary

What this Trial Is About

Randomized clinical trial to evaluate the effect of two probiotic strains which belong to Bifidobacterium Longum and Pediococcus pentosaceus species on fecal microbiota composition in healthy infants. Secondary outcomes comprise evaluation of anthropometric growth, digestive tolerance, sleeping habits, incidence of functional gastrointestinal disorders, incidence of gastrointestinal and respiratory infections, allergic reactions and safety and tolerability of the product.

CONDITIONS

Official Title

Effect of Probiotics on Infant's Fecal Microbiota Composition

Who Can Participate

Age: 1Day - 90Days
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy infants
  • Age between 1 and 90 days
  • Gestational age between 37 and 42 weeks
  • Appropriate birth weight for gestational age (between P10 and P90)
  • APGAR test score of 7-10 at 1 and 5 minutes after birth
  • Parents willing to follow study procedures and provide signed informed consent
Not Eligible

You will not qualify if you...

  • Participation in another clinical study
  • Infants fed with formula or supplements containing probiotics within 4 weeks prior to study start
  • Infants who have taken antibiotics within 4 weeks prior to study start
  • Infants with cow's milk protein allergy, lactose intolerance, or other digestive diseases
  • Maternal history of neurologic disorders, metabolic diseases, type 1 diabetes, chronic diseases, or malnutrition during pregnancy
  • Acute congenital or acquired diseases affecting growth or feeding
  • TORCH complex infections
  • Any disease related to the immune system
  • Parents unable to comply with study follow-up requirements

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Instituto Nacional de Pediatría Insurgentes Sur 3700-C, Insurgentes Cuicuilco

Alcaldía Coyoacán, Puebla, Mexico, 04530

Not Yet Recruiting

2

Clínica Viamed Montecanal

Zaragoza, Aragon, Spain, 50012

Actively Recruiting

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Research Team

G

Gerardo Rodríguez Martínez, MD

CONTACT

M

Meritxell Aguilo Garcia, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

3

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