Actively Recruiting

Age: 19Years - 35Years
All Genders
Healthy Volunteers
NCT07273123

The Effect of Prolonged Sugar-Free Chewing Gum Mastication on Self-Reported Fatigue Levels and Changes of Static and Dynamic Surface Electromyography Parameters in Young Individuals With and Without Temporomandibular Joint Disorders.

Led by University of Milan · Updated on 2026-05-01

30

Participants Needed

1

Research Sites

43 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This case-control study investigates fatigue induced by prolonged gum mastication in individuals with temporomandibular disorders (TMD). The study addresses two primary questions: How does self-reported fatigue, measured with a visual analogue scale (VAS), change during sustained chewing? How do static and dynamic surface electromyographic (sEMG) parameters evolve over the same period? Participants with TMD will be compared with healthy controls to determine group differences in perceived fatigue and EMG responses. All participants will undergo baseline EMG assessment, then chew sugar-free gum continuously for 3 minutes, alternating sides without rest. After each 3-minute interval, static and dynamic EMG recordings will be obtained and participants will rate their fatigue on the VAS. This cycle may be repeated up to six times (maximum 18 minutes). Participants are free to stop chewing at any time if fatigue becomes intolerable.

CONDITIONS

Official Title

The Effect of Prolonged Sugar-Free Chewing Gum Mastication on Self-Reported Fatigue Levels and Changes of Static and Dynamic Surface Electromyography Parameters in Young Individuals With and Without Temporomandibular Joint Disorders.

Who Can Participate

Age: 19Years - 35Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 19-35 years
  • Chewing-gum users, even occasional
  • Good general health
  • Good oral health
  • For healthy controls: no diagnosed temporomandibular joint disorders
  • For study group: diagnosed temporomandibular joint disorders
Not Eligible

You will not qualify if you...

  • Non chewing gum users
  • History of neurological disorders
  • History of musculoskeletal diseases
  • History of facial or cervical injuries
  • Presence of cervical pain
  • Two or more missing teeth
  • Current treatment with fixed or removable orthodontic appliances
  • Active periodontal disease
  • Presence of cavitated carious lesions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Milan

Milan, Milan, Italy, 20142

Actively Recruiting

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Research Team

A

Aesha Allam, DDS

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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