Preventing Postoperative Delirium with 40Hz Transcranial Stimulation in Elderly Patients Having Elective Gastrointestinal Surgery in AICU

What this Trial Is About

Postoperative delirium is a sudden brain dysfunction that affects elderly patients after surgery, marked by changes in consciousness, attention, thinking, and sleep cycles. It is a common complication among older adults, especially those receiving mechanical ventilation in intensive care. Researchers are studying the effect of exogenous 40Hz stimulation on the occurrence of postoperative delirium in elderly patients having planned gastrointestinal surgery in the acute intensive care unit AICU. Participants are randomly assigned to one of two groups after admission to AICU the experimental group receives 40Hz transcranial stimulation for 6 hours, while the control group does not receive this stimulation. This 40Hz stimulation is a physical device intervention that can influence brain activity and is thought to reduce markers linked to cognitive decline. The study is designed with quadruple masking to compare these groups effectively. During the study, researchers monitor participants for postoperative delirium daily from the first to the seventh day after surgery. They also assess blood markers at several time points after transfer to AICU, evaluate sleep quality each morning for the first three days, and track pain occurrence at 6, 24, and 48 hours post-surgery. This comprehensive monitoring aims to understand the impact of 40Hz stimulation on cognitive function and recovery in elderly surgical patients.

Effect of Prophylactic Application of 40Hz Transcranial Stimulation in AICU on Incidence of Postoperative Delirium in Elderly Patients Undergoing Elective Gastrointestinal Surgery