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Evaluating the Impact of PROSE and Scleral Lenses on Mental Health in Adults with Ocular Surface Disease
Led by Boston Sight · Updated on 2026-01-05
200
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
This research aims to evaluate how the prosthetic replacement of the ocular surface ecosystem PROSE treatment may affect mental health, focusing on mood disorders like depression. It explores the connection between changes in mental health and improvements in eye symptoms or vision. PROSE is used for certain eye surface diseases, including dry eye and ocular Graft versus Host Disease, which are linked to mental health challenges due to pain and vision loss risks. PROSE treatment involves customizing a rigid gas permeable scleral lens that protects and lubricates the eye by filling it daily with preservative-free saline. This treatment is designed to reduce eye pain, prevent damage, and improve vision. The study follows patients considering PROSE or scleral lenses for their eye conditions, assessing their mental health and eye symptoms over time. Participants will be assessed using questionnaires measuring depression PHQ-9, eye symptom severity Ocular Surface Disease Index, and quality of life Visual Function Questionnaire 25 at enrollment and at 28 and 84 days after receiving PROSE treatment. The study collects data to understand how eye treatment might relate to changes in mood and daily functioning over six months.
CONDITIONS
Brief Title
The Effect of PROSE or Scleral Lenses on Mental Health
Research Team
E
Estelle Crowley, BS
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