Actively Recruiting
Effect of Regional Anesthesia or Intravenous Infusion of Lidocaine on Morphine Use After Scoliosis Repair Surgery
Led by Assaf-Harofeh Medical Center · Updated on 2024-11-12
105
Participants Needed
1
Research Sites
108 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of the surgical correction of scoliosis is to prevent progression of the curve or progression of restrictive lung disease. After scoliosis surgery, patients experience severe pain. The standard treatment for pain relief after scoliosis surgery is the administration of opiates. However, treatment with these substances involves side effects such as respiratory depression, nausea and vomiting, inhibition of bowel activity and itching. To lower the dose of opiates, different types of painkillers and other techniques can be added. The purpose of the study is to compare the effect of instillation of lidocaine (which is an analgesic and anti-inflammatory) or regional anesthesia using Erector spinae plane on the dose of morphine consumption, the intensity of pain, the side effects and the quality of recovery during the first 48 hours after surgery to repair scoliosis.
CONDITIONS
Official Title
Effect of Regional Anesthesia or Intravenous Infusion of Lidocaine on Morphine Use After Scoliosis Repair Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 12 to 25 years with normal cognition scheduled for scoliosis correction surgery
- Patients able to use intravenous patient-controlled analgesia (PCA) independently
- Signed informed consent by the patient or parent/guardian if a minor
You will not qualify if you...
- Patients who do not agree to participate despite parental consent
- Patients unable to independently operate the PCA device
- Patients using opioids or cannabis for chronic pain for more than one month
- Current drug use of any kind
- Alcoholism
- Patients with depression, anxiety, or post-trauma
- Moderate to severe respiratory, cardiac, liver, or kidney failure
- Sensitivity to any drug used in the study protocol
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shamir (Asaf Harofe) Medical Center
Be’er Ya‘aqov, Israel, 70300
Actively Recruiting
Research Team
S
Sara Bar Yehuda, PhD
CONTACT
Z
Zoya Haitov Ben Zikri, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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