Actively Recruiting
Comparing Regional Anesthesia with Erector Spinae Plane Block and Intravenous Lidocaine Infusion to Reduce Morphine Use After Scoliosis Surgery
Led by Assaf-Harofeh Medical Center · Updated on 2024-11-12
105
Participants Needed
1
Research Sites
13 weeks
Total Duration
AI-Summary
What this Trial Is About
The trial investigates pain management methods following scoliosis repair surgery, aiming to prevent worsening spinal curvature and lung restriction. After surgery, patients often experience severe pain typically treated with morphine via a patient-controlled analgesia PCA device. Because morphine and similar opioids can cause side effects like breathing problems, nausea, vomiting, bowel issues, and itching, this study compares two additional pain relief techniques to reduce morphine use and improve recovery quality within 48 hours after surgery. Participants will be randomly assigned to one of three groups. The control group receives standard general anesthesia without additional interventions. The second group receives general anesthesia plus an ultrasound-guided erector spinae plane ESP block to provide regional anesthesia. The third group receives general anesthesia plus a continuous intravenous infusion of lidocaine starting after anesthesia induction and continuing for 24 hours. Morphine use is controlled by the PCA device, which patients operate themselves to manage pain. Participants will be monitored for 48 hours post-surgery to measure morphine consumption and pain levels at multiple time points. Researchers will also record side effects such as nausea, time to first bowel movement, and time to first walk. Quality of recovery will be assessed using the QOR-15 questionnaire 72 hours after surgery. Demographic and clinical data will be collected to evaluate safety and effectiveness of the pain management approaches during the study period.
CONDITIONS
Brief Title
Effect of Regional Anesthesia or Intravenous Infusion of Lidocaine on Morphine Use After Scoliosis Repair Surgery
Research Team
S
Sara Bar Yehuda, PhD
Z
Zoya Haitov Ben Zikri, MD
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