Actively Recruiting
Effect of Resistance Exercise on Energy Balance and Appetite Regulation in Males and Females
Led by National Taiwan Normal University · Updated on 2026-03-02
30
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying how resistance exercise affects appetite regulation and energy balance in healthy males and females aged 20 to 30 years. This research also aims to identify any sex-based differences in how these responses occur, recognizing that males and females may react differently to exercise. Understanding these effects can help improve exercise guidelines that are tailored to both sexes. Participants perform resistance exercises including squats, bench press, and deadlift in a fixed order. Each exercise involves three sets of seven repetitions using 70% of their one-repetition maximum (1RM), with 120 seconds of rest between sets. Females complete these exercises during the early follicular phase of their menstrual cycle. On control days, participants remain seated at rest without exercising. During the study, researchers will measure subjective appetite, hormone levels like acyl-Ghrelin, PYY, and cortisol, lactate, energy intake, expenditure, and overall energy balance before, during, and after interventions. Additional assessments include food preferences, perceived exertion, heart rate, and various exercise performance metrics. The study is randomized and open-label, with a participation window from December 2025 to December 2026.
CONDITIONS
Brief Title
Effect of Resistance Exercise on Energy Balance and Appetite Regulation in Males and Females
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy males and females aged 20 to 30 years
- Females with a regular menstrual cycle
- Stable body weight with no significant change in the past 6 months
- Willingness to participate and provide written informed consent
You will not qualify if you...
- Obesity defined as BMI greater than 30 kg/m²
- Body fat percentage greater than 25% in males
- Body fat percentage greater than 30% in females
- Hypertension with resting blood pressure greater than 140/90 mmHg
- History of cardiovascular disease
- History of cancer
- History of liver disease
- History of kidney disease
- Any medical condition that may interfere with study outcomes
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Each intervention session lasts several hours with crossover between exercise and control conditions.
Participants perform resistance exercises consisting of squat, bench press, and deadlift. Each exercise includes three sets of seven repetitions at 70% of their one-repetition maximum with rest between sets. Female participants complete exercises during the early follicular phase. Control periods involve remaining seated at rest.
Multiple visits depending on crossover schedule
Trial Site Locations
Total: 1 location
1
National Taiwan Normal University
Taipei, Taiwan, 106
Actively Recruiting
Research Team
H
Hung-wen Liu, Ph.D.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
4
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