Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07558317

The Effect of Resistance Exercise in Patients With Lower Limb Lymphedema (the LymphEx Study)

Led by Carsten Bogh Juhl · Updated on 2026-05-06

36

Participants Needed

1

Research Sites

47 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of the study is to investigate the short-term (within 2 weeks) effects of resistance exercise with and without compression garments on lower limb lymphedema(LLL). Additionally, the study will explore the immediate response in LLL to resistance exercise (2 hours and 24 hours post-exercise). Participants will continously wear a circumfencential sensor at the calf (CIMON from Icompression) under a compression garment and an activity tracker (SENS Motion from SENS Innovation Aps) at the thigh for 3 periods (two with supervised exercise sessions of 2 weeks and one control period). Participants will attend supervised resistance exercise 2-3 times per week for 2 periods of 2 weeks (one with compression garment and one without). Assessments with the principal investigator will be scheduled before and after every 2 week period. Participants will keep a digital diary or diary in paper of their lymphedema related symptoms and experienced issues with the sensors or app.

CONDITIONS

Official Title

The Effect of Resistance Exercise in Patients With Lower Limb Lymphedema (the LymphEx Study)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Verified diagnosis of lymphedema of the lower limb
  • Completed compression bandaging
  • Adherence to compression garment in daytime at least 5-6 days per week
  • Calf circumference greater than 35 cm and less than 75 cm
Not Eligible

You will not qualify if you...

  • Severe neuropathy of the lower leg
  • Severe skin problems or wounds at the lower leg
  • Cellulitis, deep vein thrombosis, or acute injuries of the lower limb within 2 months prior to inclusion
  • Ongoing adjuvant treatment for cancer

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Herlev and Gentofte Hospital, Department of Physiotherapy and Occupational Therapy

Herlev, Denmark, 2730

Actively Recruiting

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Research Team

M

Merete C Wittenkamp, PhD student

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

3

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The Effect of Resistance Exercise in Patients With Lower Limb Lymphedema (the LymphEx Study) | DecenTrialz