Actively Recruiting
The Effect of Retrograde Autologous Priming on Transfusion Requirements After Cardiac Surgery
Led by Population Health Research Institute · Updated on 2025-03-04
4500
Participants Needed
4
Research Sites
99 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The TheRAPy vanguard trial is a multicentre, multiple period randomized, cluster crossover vanguard trial testing the feasibility of a full-scale trial to evaluate whether a centre-based policy of routine use of RAP versus a policy of crystalloid priming reduces RBC transfusion for patients undergoing cardiac surgery on cardiopulmonary bypass. It will also provide information about key parameters of the TheRAPy full-scale trial.
CONDITIONS
Official Title
The Effect of Retrograde Autologous Priming on Transfusion Requirements After Cardiac Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Hospitals completing >200 adult cardiac surgical cases a year
- At least 95% of the cardiovascular surgery group agrees to manage patients under both autologous priming policies as per the randomization schedule
- All patients undergoing cardiac surgery on cardiopulmonary bypass at an enrolled site during the trial period will be included in data collection
You will not qualify if you...
- Hospitals completing ≤200 cardiac surgical cases
- Less than 95% of the cardiovascular surgery group agrees to manage patients according to either of the two policies
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
St. Boniface Hospital
Winnipeg, Manitoba, Canada, R2H 2A6
Actively Recruiting
2
Hamilton General Hospital
Hamilton, Ontario, Canada, L8S 48L
Actively Recruiting
3
Montreal Heart Institute
Montreal, Quebec, Canada, H1T 1C8
Actively Recruiting
4
Centre Hospitalier de l'Université de Montréal (CHUM)
Montreal, Quebec, Canada, H2X 0A9
Actively Recruiting
Research Team
T
TheRAPy Study Coordinator
CONTACT
J
Jessica Spence
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
OTHER
Number of Arms
2
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