Actively Recruiting

Early Phase 1
Age: 18Years +
All Genders
NCT07116421

Effect of Rose Odor Exposure on Ictal Apnea

Led by Vanderbilt University Medical Center · Updated on 2025-08-11

40

Participants Needed

1

Research Sites

44 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study will investigate the potential benefits of rose scent in reducing the risk of Sudden Unexpected Death in Epilepsy (SUDEP) in patients with epilepsy. Participants will engage in their routine inpatient observational EEG monitoring for 24 hours followed by an additional 24 hours of observational EEG monitoring with continuous exposure to rose scent, during which an essential oil diffusor with rose scent will be placed in their hospital room. During these 48 total hours of the study, participants will wear a respiratory monitoring belt across their upper chest to measure their breathing. Potential risks include distress or discomfort when smelling the rose scent used in the study, a physical reaction to the rose scent, and discomfort or feelings of restrictiveness when wearing the respiratory monitoring belt. The total time commitment of the study is 48 consecutive hours over the course of the participants' inpatient EMU stay, during which there will be no restrictions on daily activities during the standard inpatient EMU admission except that participants must wear their respiratory belt for a majority of this 2-day period.

CONDITIONS

Official Title

Effect of Rose Odor Exposure on Ictal Apnea

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult epilepsy patients over the age of 18
  • Admission to the inpatient epilepsy monitoring unit (EMU) at Vanderbilt University Medical Center (VUMC)
  • Undergoing observational EEG monitoring without treatment involving seizure medication changes or other interventions for at least 48 hours
Not Eligible

You will not qualify if you...

  • Patients under the age of 18
  • Patients receiving EEG monitoring without interventions from baseline for less than 48 hours
  • Patients who are not receiving EEG monitoring as a part of their inpatient admission.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Vanderbilt University Medical Center

Nashville, Tennessee, United States, 37232

Actively Recruiting

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Research Team

B

Brigitte Jia, BA

CONTACT

W

William P Nobis, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

PREVENTION

Number of Arms

2

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Effect of Rose Odor Exposure on Ictal Apnea | DecenTrialz