Actively Recruiting

Phase Not Applicable
Age: 20Years - 65Years
All Genders
NCT07091981

Effect of Rotary File Number on MB2 Canal Negotiation and Postoperative Pain

Led by Mehmet Adıgüzel · Updated on 2025-08-01

152

Participants Needed

1

Research Sites

11 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This randomized controlled clinical trial aims to evaluate the effect of the number of rotary files on working length negotiation and postoperative pain in the second mesiobuccal (MB2) canals of maxillary first molars. Patients are assigned to one of four groups according to the number of rotary files used: single-, two-, three-, or four-file systems. Postoperative pain is assessed on each of the seven consecutive postoperative days (Days 1-7) using a visual analog scale (VAS), and working length negotiation success is recorded during canal instrumentation.

CONDITIONS

Official Title

Effect of Rotary File Number on MB2 Canal Negotiation and Postoperative Pain

Who Can Participate

Age: 20Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Systemically healthy individuals aged between 20 and 65 years
  • Requiring primary endodontic treatment of maxillary first molars
  • Diagnosis of asymptomatic apical periodontitis and pulp necrosis based on clinical and radiographic findings
  • Presence of a second mesiobuccal (MB2) canal in the maxillary first molar
  • Absence of or only minimal preoperative pain or symptoms
  • Periapical lesions smaller than 5 mm in diameter
  • Ability to comply with follow-up visits and effectively communicate during the treatment process
Not Eligible

You will not qualify if you...

  • Presence of symptomatic apical periodontitis or acute apical abscess
  • Retreatment cases (teeth previously treated endodontically)
  • Use of medications such as narcotics, antibiotics, sedatives, or antidepressants within one week prior to treatment
  • Presence of a sinus tract, periapical abscess, or facial cellulitis
  • Pregnancy or breastfeeding
  • Inability to understand or follow the study instructions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hatay Mustafa Kemal University Faculty of Dentistry

Antakya, Hatay, Turkey (Türkiye), 31006

Actively Recruiting

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Research Team

M

Mehmet A. Adıgüzel, DDS, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

4

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Effect of Rotary File Number on MB2 Canal Negotiation and Postoperative Pain | DecenTrialz