Actively Recruiting
Effect of Number of Rotary Instruments on Negotiating Second Mesiobuccal Canals to Working Length and on Postoperative Pain: A Randomized Clinical Trial
Led by Mehmet Adıgüzel · Updated on 2025-08-01
152
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating how the number of rotary files used during root canal treatment affects the ability to reach the full working length in the second mesiobuccal (MB2) canals of maxillary first molars and the level of pain experienced after the procedure. This randomized clinical trial compares single-file, two-file, three-file, and four-file rotary systems. The study focuses on patients needing primary endodontic treatment for maxillary first molars with pulp necrosis and asymptomatic apical periodontitis. Participants receive root canal treatments using one of four different rotary file systems. The single-file group uses the OneCurve system at 300 rpm and 2.5 Ncm torque. The two-file system applies the Perfect Minimally Invasive Kit with files used sequentially at similar speeds and torque under continuous irrigation. The three-file system employs VDW Rotate files with brushing-pecking motions, while the four-file system uses the Perfect Advanced Kit in a crown-down technique with specific rpm and torque settings. Each instrumentation step includes irrigation and cleaning to avoid debris buildup. During the study, postoperative pain is assessed daily for seven days using a visual analog scale (VAS). Success in negotiating the working length in the MB2 canal is recorded during treatment. Participants are monitored for pain intensity and treatment progress, with follow-up visits to evaluate outcomes. The study runs from June 18, 2025, to September 5, 2025, with patients aged 20 to 65 years included based on specific dental health criteria.
CONDITIONS
Brief Title
Effect of Rotary File Number on MB2 Canal Negotiation and Postoperative Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Systemically healthy individuals aged between 20 and 65 years
- Requiring primary endodontic treatment of maxillary first molars
- Diagnosis of asymptomatic apical periodontitis and pulp necrosis based on clinical and radiographic findings
- Presence of a second mesiobuccal (MB2) canal in the maxillary first molar
- Absence of or only minimal preoperative pain or symptoms
- Periapical lesions smaller than 5 mm in diameter
- Ability to comply with follow-up visits and effectively communicate during the treatment process
You will not qualify if you...
- Presence of symptomatic apical periodontitis or acute apical abscess
- Retreatment cases (teeth previously treated endodontically)
- Use of medications such as narcotics, antibiotics, sedatives, or antidepressants within one week prior to treatment
- Presence of a sinus tract, periapical abscess, or facial cellulitis
- Pregnancy or breastfeeding
- Inability to understand or follow the study instructions
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single treatment session
Participants receive root canal treatment using one of four rotary file systems applied to the MB2 canals of maxillary first molars. The instrumentation involves different numbers of rotary files operated at specified speeds and torque settings with irrigation and brushing-pecking motions as appropriate.
1 visit (in-person)
Duration - 7 days
Participants report their postoperative pain intensity daily for 7 consecutive days following the root canal treatment.
Daily assessments for 7 days
Trial Site Locations
Total: 1 location
1
Hatay Mustafa Kemal University Faculty of Dentistry
Antakya, Hatay, Turkey (Türkiye), 31006
Actively Recruiting
Research Team
M
Mehmet A. Adıgüzel, DDS, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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