Actively Recruiting

Phase 2
Age: 18Years - 75Years
All Genders
NCT07364786

Effect of Salovum® on Pressure, Oxygen and Inflammation in Glioblastoma

Led by Peter Siesjö · Updated on 2026-01-23

10

Participants Needed

1

Research Sites

107 weeks

Total Duration

On this page

Sponsors

P

Peter Siesjö

Lead Sponsor

L

Lund University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The objective of this clinical trial is to investigate the effects of Salovum®, an egg yolk powder enriched with the endogenous protein antisecretory factor, in participants undergoing diagnostic biopsies for suspected glioblastoma. The primary questions the trial seeks to answer are: * Will Salovum® reduce intratumoral pressure? * Will Salovum® influence the release of inflammatory cytokines from tumor tissue? Additionally, the study will investigate the impact of Salovum® on intratumoral partial oxygen pressure and tumor volume. Researchers will: * Place probes for measuring intratumoral pressure, microdialysis, and partial oxygen pressure during a standard biopsy procedure. * Compare measurements from participants before and during ingestion of Salovum®. Participants will: * Have probes implanted during a surgical biopsy. * Ingest Salovum® 24 to 72 hours after the procedure.

CONDITIONS

Official Title

Effect of Salovum® on Pressure, Oxygen and Inflammation in Glioblastoma

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Suspected glioblastoma
  • Age 18 to 75 years
  • Planned diagnostic biopsy
  • Provided informed consent
Not Eligible

You will not qualify if you...

  • Known allergy to egg yolk

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Department of Neurosurgery, Skane University Hospital

Lund, Sweden, 221 85

Actively Recruiting

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Research Team

P

Peter Siesjö, MD, PhD.

CONTACT

E

Erik Ehinger, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SEQUENTIAL

Primary Purpose

TREATMENT

Number of Arms

1

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