Actively Recruiting
Effect of Salovum® on Pressure, Oxygen and Inflammation in Glioblastoma
Led by Peter Siesjö · Updated on 2026-01-23
10
Participants Needed
1
Research Sites
107 weeks
Total Duration
On this page
Sponsors
P
Peter Siesjö
Lead Sponsor
L
Lund University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The objective of this clinical trial is to investigate the effects of Salovum®, an egg yolk powder enriched with the endogenous protein antisecretory factor, in participants undergoing diagnostic biopsies for suspected glioblastoma. The primary questions the trial seeks to answer are: * Will Salovum® reduce intratumoral pressure? * Will Salovum® influence the release of inflammatory cytokines from tumor tissue? Additionally, the study will investigate the impact of Salovum® on intratumoral partial oxygen pressure and tumor volume. Researchers will: * Place probes for measuring intratumoral pressure, microdialysis, and partial oxygen pressure during a standard biopsy procedure. * Compare measurements from participants before and during ingestion of Salovum®. Participants will: * Have probes implanted during a surgical biopsy. * Ingest Salovum® 24 to 72 hours after the procedure.
CONDITIONS
Official Title
Effect of Salovum® on Pressure, Oxygen and Inflammation in Glioblastoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Suspected glioblastoma
- Age 18 to 75 years
- Planned diagnostic biopsy
- Provided informed consent
You will not qualify if you...
- Known allergy to egg yolk
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Neurosurgery, Skane University Hospital
Lund, Sweden, 221 85
Actively Recruiting
Research Team
P
Peter Siesjö, MD, PhD.
CONTACT
E
Erik Ehinger, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SEQUENTIAL
Primary Purpose
TREATMENT
Number of Arms
1
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