Actively Recruiting

Phase Not Applicable
Age: 18Years - 35Years
All Genders
NCT07318987

EFFECT OF SAPHENOUS NERVE RELEASE ON PATIENTS WITH PATELLOFEMORAL PAIN SYNDROME

Led by Cairo University · Updated on 2026-01-06

36

Participants Needed

1

Research Sites

15 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Patellofemoral Pain Syndrome (PFPS) is a frequent cause of anterior knee pain in young, physically active individuals, especially females, and is commonly managed with quadriceps and hip-focused exercises. However, the role of neural factors has been largely overlooked. The saphenous nerve, which supplies sensation to the anteromedial knee, may become irritated or entrapped and contribute to pain and neuromuscular dysfunction in PFPS. This study suggests that manual therapy targeting the saphenous nerve could improve pain, function, and balance, providing a more holistic approach to PFPS rehabilitation.

CONDITIONS

Official Title

EFFECT OF SAPHENOUS NERVE RELEASE ON PATIENTS WITH PATELLOFEMORAL PAIN SYNDROME

Who Can Participate

Age: 18Years - 35Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age from 18 to 35 years and BMI 18 to 25 kg/m2
  • Both male and female genders
  • Anterior knee pain lasting at least six weeks
  • Positive saphenous neurodynamic test (SAPHNT)
Not Eligible

You will not qualify if you...

  • History of knee replacement
  • Received an intraarticular injection within the past 3 months
  • Previous knee surgery or arthroscopy
  • Other secondary knee problems such as bursitis, tendinopathy, osteochondritis, neuromas, intraarticular pathology including osteoarthritis, tumor, or rheumatologic diseases
  • Diabetic neuropathic pain or fibromyalgia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Faculty of Physical Therapy, Cairo University

Cairo, Egypt

Actively Recruiting

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Research Team

M

Markos Boshra, bachelor's

CONTACT

M

Markos Boshra, bachelor's

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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