Actively Recruiting
Effect of Saphenous Nerve Release on Pain, Balance, and Function in Patients with Patellofemoral Pain Syndrome
Led by Cairo University · Updated on 2026-01-06
36
Participants Needed
1
Research Sites
2 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Patellofemoral Pain Syndrome (PFPS) is a common cause of front knee pain, especially in young, active people and more often in females. This condition is usually treated with exercises focusing on the quadriceps and hips. However, this study explores the role of the saphenous nerve, which provides sensation to the inner knee and may become irritated, contributing to pain and muscle control problems in PFPS. The study aims to see if targeting this nerve with manual therapy can improve pain, function, and balance for a more complete treatment approach. The study compares two treatments: one group will receive manual therapy called saphenous nerve release, where a therapist gently mobilizes a sensitive area near the knee to reduce nerve irritation. The other group will undergo traditional treatment including exercises to strengthen the hip and knee muscles, manual patellar joint mobilization, and stretching. These exercises are done three times a week for six weeks, with increasing repetitions and resistance. Treatments are carried out with the patient lying or sitting as appropriate. Participants will be assessed over six weeks for changes in knee pain, balance, and function. Measurements like the Q angle of the knee will also be tracked. The study uses questionnaires and physical tests to monitor progress. Safety and effectiveness will be evaluated through these outcomes. The total participation lasts six weeks, during which researchers carefully observe the effects of the nerve release compared to traditional therapy.
CONDITIONS
Brief Title
EFFECT OF SAPHENOUS NERVE RELEASE ON PATIENTS WITH PATELLOFEMORAL PAIN SYNDROME
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age from 18 to 35 years and body mass index between 18 and 25 kg/m2
- Both males and females are eligible
- Have had anterior knee pain for at least six weeks
- Positive saphenous neurodynamic test (SAPHNT)
You will not qualify if you...
- History of knee replacement surgery
- Intraarticular knee injection within the past 3 months
- Previous knee surgery, arthroscopy, or secondary knee problems like bursitis, tendinopathy, osteochondritis, neuromas, osteoarthritis, tumors, or rheumatologic diseases
- Diabetic neuropathic pain or fibromyalgia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 weeks
Participants receive either saphenous nerve release therapy or traditional treatment involving strengthening, manual therapy, and stretching exercises targeting the hip and knee.
3 visits per week for 6 weeks
Trial Site Locations
Total: 1 location
1
Faculty of Physical Therapy, Cairo University
Cairo, Egypt
Actively Recruiting
Research Team
M
Markos Boshra, bachelor's
M
Markos Boshra, bachelor's
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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