Actively Recruiting
Effect of Sevoflurane vs Desflurane on Mechanical Power in Laparoscopic Cholecystectomy
Led by Konya City Hospital · Updated on 2026-03-13
138
Participants Needed
1
Research Sites
11 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This single-center, prospective, randomized, assessor-blinded clinical trial aims to compare the effects of sevoflurane and desflurane anesthesia on intraoperative mechanical power in adult patients undergoing elective laparoscopic cholecystectomy. Mechanical power will be measured at three standardized time points using a validated formula, and secondary outcomes include driving pressure values and early postoperative respiratory complications (desaturation, laryngospasm, bronchospasm, cough).
CONDITIONS
Official Title
Effect of Sevoflurane vs Desflurane on Mechanical Power in Laparoscopic Cholecystectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18-65 years
- ASA Physical Status I-II
- Scheduled for elective laparoscopic cholecystectomy
- Able to provide written informed consent
You will not qualify if you...
- Known hypersensitivity or contraindication to sevoflurane or desflurane
- Severe chronic obstructive pulmonary disease (COPD)
- Uncontrolled bronchial asthma
- Decompensated heart failure (NYHA Class III-IV)
- History of prior lung surgery
- Morbid obesity (BMI > 35 kg/m²)
- Pregnancy
- Refusal to participate or inability to provide informed consent
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Konya City Hospital
Konya, Konya, Turkey (Türkiye), 42020
Actively Recruiting
Research Team
N
Nuran AKINCI EKİNCİ
CONTACT
E
Esma Karaarslan
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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