Study of Silver Diamine Fluoride to Improve Local Anesthesia in Children With Hypomineralized Permanent Molars

What this Trial Is About

Molar incisor hypomineralization MIH is a tooth enamel defect that affects permanent molars and incisors, causing sensitivity and rapid dental caries progression. This research aims to evaluate whether applying 38% silver diamine fluoride SDF before dental treatment improves the effectiveness of local anesthesia in children with MIH, addressing challenges in managing pain during treatment. The trial is randomized and controlled to help develop better treatment protocols for affected molars. Participants will receive either 38% SDF or an inert liquid as a placebo applied to the affected molar two weeks before restorative dental care. This pre-treatment aims to reduce tooth sensitivity by blocking dentinal tubules and promoting remineralization, potentially improving anesthesia efficacy and reducing pain during procedures. During the study, children will undergo dental treatment on the treated molars after the two-week period. Researchers will assess anesthesia effectiveness using the Sixou and Barbosa-Rogier scale and measure tooth sensitivity with the Schiff Cold Air Sensitivity Scale. The study includes monitoring for adverse reactions and aims to provide data to improve pain management in teeth affected by MIH.

Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars