Actively Recruiting
Effect of Snacks on Aging
Led by University of California, Los Angeles · Updated on 2025-05-28
60
Participants Needed
1
Research Sites
58 weeks
Total Duration
On this page
Sponsors
U
University of California, Los Angeles
Lead Sponsor
A
American Pecan Promotion Board
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to determine if daily consumption of 2 oz of pecans compared to 3.5 oz pretzel snacks for 12 weeks will 1) contribute to the body's ability to protect itself from oxidative damage (caused by oxygen radicals created by ultraviolet (UV) B light) by evaluating skin resistance to UV light irritation, skin fats/oils degradation and "rusting", and oxidative damage to the skin genes; and 2) explore the mechanisms of how snack consumption may affect aging by analyzing blood markers of aging as well as the microbes living in the gut (gut microbiome).
CONDITIONS
Official Title
Effect of Snacks on Aging
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female
- Generally healthy
- Aged 55 to 75 years
- Body mass index (BMI) between 18.5 and 34.9 kg/m2
- Fitzpatrick skin type II-IV
- Consume a typical Western diet low in polyphenol-rich foods and fiber
- Willing to maintain usual diet and exercise habits during the study
- Willing to keep normal skin care products and routine during the study
- Willing to attend study visits without makeup or skin products
- Able to read and sign informed consent before joining the study
You will not qualify if you...
- Vegetarian or vegan diet
- Known allergy to nuts
- Use of skin-related prescription medications, supplements, or cosmeceutical agents
- Started topical or oral prescription steroids or anti-inflammatory medications within 30 days before enrollment
- Excessive exposure to natural or artificial sunlight
- Abnormal screening laboratory values considered clinically significant
- Any documented chronic disease
- Use of medications or supplements affecting gut microbiota (e.g., antibiotics in past 3 months, probiotics, fiber)
- Use of exogenous hormones such as hormone replacement therapy
- Weight changes greater than 10% in the last 6 months
- Smoker or living with a smoker
- Consuming more than 20 grams of alcohol per day
- Unable or unwilling to comply with study protocol, including avoiding nuts during the study
- Unable to provide informed consent
- Pregnancy or breastfeeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UCLA Center for Human Nutrition
Los Angeles, California, United States, 90095
Actively Recruiting
Research Team
T
Tatiana Diacova, PhD, RD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here