Actively Recruiting
Effect of Sodium-glucose Cotransporter-2 Inhibitors (SGLT-2i) on Proteinuria in Nephrotic Children Older Than 10 Years
Led by Mansoura University · Updated on 2024-05-16
60
Participants Needed
1
Research Sites
113 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to evaluate the effect of ACE inhibitors and SGLT-2 inhibitors on: 1. Proteinuria 2. Renal survival indices
CONDITIONS
Official Title
Effect of Sodium-glucose Cotransporter-2 Inhibitors (SGLT-2i) on Proteinuria in Nephrotic Children Older Than 10 Years
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 10 and 18 years old
- Nephrotic syndrome resistant to treatment
- No history of diabetes
- Estimated glomerular filtration rate (eGFR) of 60 ml/min/1.73m2 or higher, calculated by Schwartz formula
- Caregivers agree to have the child participate in the study
You will not qualify if you...
- Uncontrolled urinary tract infection at screening
- Blood pressure below the 5th percentile for gender, age, and height
- Risk of dehydration or low blood volume
- Liver disease indicated by liver enzyme levels more than twice the normal limit at screening
- History of organ transplant, cancer, or liver disease
- History of not following medical treatments or unwillingness to comply with the study protocol
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mansoura University Children's Hospital
Al Mansurah, Dakahlia Governorate, Egypt, 35516
Actively Recruiting
Research Team
A
Ayman Hammad, MBBCh,MSc,MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here