Actively Recruiting

Phase Not Applicable
Age: 60Years - 80Years
All Genders
NCT07449117

Effect of Striatal Temporal Interference Stimulation on Language Processing in Neurodegenerative Diseases

Led by Masaryk University · Updated on 2026-03-04

70

Participants Needed

1

Research Sites

143 weeks

Total Duration

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AI-Summary

What this Trial Is About

The purpose of this study is to investigate the immediate effects of non-invasive temporal interference stimulation (TIS) targeting the striatum on sentence processing and brain connectivity in patients with neurodegenerative diseases.

CONDITIONS

Official Title

Effect of Striatal Temporal Interference Stimulation on Language Processing in Neurodegenerative Diseases

Who Can Participate

Age: 60Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of possible or probable Mild Cognitive Impairment with Lewy Bodies (MCI-LB), Parkinson's Disease with Mild Cognitive Impairment (MCI-PD), or Amnestic Mild Cognitive Impairment (aMCI)
Not Eligible

You will not qualify if you...

  • Presence of any severe psychiatric disorder
  • History of neurological diseases affecting the central nervous system other than the target conditions
  • History of severe head trauma
  • Uncompensated internal or oncological disease
  • Presence of MRI-incompatible metal in the body (e.g., pacemaker)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CEITEC MU (Central European Institute of Technology, Masaryk University)

Brno, South Moravian, Czechia, 625 00

Actively Recruiting

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Research Team

Ľ

Ľubomíra Nováková, Ph.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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