Actively Recruiting

Phase Not Applicable
Age: 55Years +
All Genders
NCT06084949

Effect of Structured Exercise in Patients With Knee Osteoarthritis

Led by The Hong Kong Polytechnic University · Updated on 2023-10-16

80

Participants Needed

1

Research Sites

151 weeks

Total Duration

On this page

Sponsors

T

The Hong Kong Polytechnic University

Lead Sponsor

K

Kwong Wah Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

The aim of this randomized controlled trial is to evaluate the effect of Nordic walking and inspiratory muscle training (IMT) on cardiopulmonary function in patients with knee osteoarthritis (OA). Mild-to-moderate knee OA patients are randomly allocated into Experimental group (Nordic walking plus routine management) or Control group (Routine management). While End-stage knee OA patients are randomly allocated into Experimental group (IMT plus pre-operative rehabilitation exercise) or Control group (Pre-operative rehabilitation exercise). Participants are invited to undergo two assessments, including baseline assessment, post-intervention assessment. Researchers will compare two groups to see if the cardiopulmonary function can be improved after intervention.

CONDITIONS

Official Title

Effect of Structured Exercise in Patients With Knee Osteoarthritis

Who Can Participate

Age: 55Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Pain on most days in one or both knees in the past month
  • Difficulty with at least one daily living activity measured by the WOMAC scale
  • Radiographic evidence of knee OA in the tibial-femoral compartment (Kellgren and Lawrence grade 1-3 for mild-to-moderate; others waiting for knee arthroplasty as end-stage)
  • Normal or corrected vision and hearing and able to walk unaided
  • Primary knee OA for more than 6 months, stable on medication for at least 3 weeks
Not Eligible

You will not qualify if you...

  • Prior knee surgery
  • Steroid injection within the previous three weeks
  • Inflammatory arthritis (e.g., rheumatoid arthritis), unstable angina, myocardial infarction, cardiac surgery, stroke
  • Treatment with steroids, hormones, or cancer chemotherapy
  • Pulmonary diseases with specific lung function limits or history of exercise-induced asthma
  • Unable to understand study procedures and risks
  • Medically unstable and unsafe for exercise testing

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Hong Kong Polytechnic University

Kowloon City, Kowloon, Hong Kong

Actively Recruiting

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Research Team

T

Tracy Tang

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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