Actively Recruiting

Age: 6Years - 15Years
All Genders
NCT05885646

Effect of Sulthiame on EEG in Childhood Epilepsy Syndromes

Led by University Hospital, Angers · Updated on 2025-06-15

15

Participants Needed

3

Research Sites

110 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The effect of sulthiame on EEG has been studied in epilepsy syndromes of childhood with sleep activation by comparing sleep EEG obtained at baseline and after 4 weeks of treatment. The aim of the study is to know if an effect is still identifiable after 2 weeks of treatment by performing sleep EEG recordings after 2 and 4 weeks of treatment, respectively.

CONDITIONS

Official Title

Effect of Sulthiame on EEG in Childhood Epilepsy Syndromes

Who Can Participate

Age: 6Years - 15Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of epilepsy syndromes of childhood with sleep activation
  • Failure of at least two anti-epileptic drugs (AED)
  • Sleep EEG performed in the last 7 days before inclusion and showing interictal epileptiform discharges (baseline EEG)
Not Eligible

You will not qualify if you...

  • Previous trial with sulthiame
  • More than 2 AED at inclusion
  • Use of corticosteroids at inclusion
  • Change in the anti-epileptic treatment in the 7 days before baseline EEG

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Angers University Hospital, Pediatric department

Angers, France, 49000

Actively Recruiting

2

Strasbourg University Hospital, Pediatric department

Strasbourg, France, 67000

Not Yet Recruiting

3

Toulouse University Hospital, Pediatric Neurology Department

Toulouse, France, 31000

Not Yet Recruiting

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Research Team

P

Patrick Van Bogaert, Professor

CONTACT

E

Elsa Berardi

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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