Actively Recruiting
Effect of Supplementation With Creatine on the Recovery of Ischemic Stroke
Led by Fundació d'investigació Sanitària de les Illes Balears · Updated on 2025-07-08
92
Participants Needed
1
Research Sites
143 weeks
Total Duration
On this page
Sponsors
F
Fundació d'investigació Sanitària de les Illes Balears
Lead Sponsor
C
Comunidad Autónoma de las Islas Baleares (Dirección General de Investigación en Salud, Formación y Acreditación)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Stroke is a leading cause of disability and the second leading cause of death worldwide. Most strokes are ischemic, caused by acute arterial occlusion. Post-stroke treatment focuses on secondary prevention and rehabilitation, but few treatments address functional recovery. Creatine, a supplement known for improving physical performance, may aid in the recovery of stroke patients, reducing sarcopenia and improving strength among other effects. This pilot study will investigate the effectiveness of creatine supplementation in enhancing physical and functional recovery in ischemic stroke patients. The study will involve a randomized, double-blind clinical trial comparing creatine monohydrate to a placebo.
CONDITIONS
Official Title
Effect of Supplementation With Creatine on the Recovery of Ischemic Stroke
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 80 years
- Recent ischemic stroke diagnosis from 24 hours to 5 days prior
- Neurological deficit from stroke affecting mobility that requires motor rehabilitation
- Ability to understand and sign informed consent or have support to follow the study
You will not qualify if you...
- Moderate to severe disability before stroke (mRS >2)
- Unstable or severe clinical condition preventing active rehabilitation
- Stroke-related neurological deficit that prevents walking without help from another person (canes, crutches, or walkers allowed)
- Moderate or severe swallowing difficulties affecting treatment adherence
- Use of creatine or anabolic supplements in the last 3 months
- Severe kidney disease (GFR <30 ml/min/1.73 m2)
- Muscle or bone conditions preventing muscle strength assessment (e.g., fractures, severe osteoarthritis, ligament tears, tendinopathies)
- History of allergic reactions to creatine
- Pregnancy or breastfeeding
- Participation in another clinical trial at the same time
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
IdISBa
Palma de Mallorca, Balearic Islands, Spain, 07120
Actively Recruiting
Research Team
R
Raquel Delgado Mederos, PhD
CONTACT
E
Eduard Bargay Pizarro, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here